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Wellcome Sanger Institute

Using genome sequences for hundreds of ancient individuals, researchers have analyzed population dynamics and displacements around the Eurasian steppe.

While digging into the tumor-suppressive mechanism for an X-linked gene called UTX, researchers found a similar protective role for the Y chromosome gene UTY.

Saturation mutagenesis of the human malaria parasite Plasmodium falciparum identified almost 2,700 essential genes during the blood stage of infection.

Scientists have sequenced more than 2,700 distinct strains from the National Collection of Type Cultures, a non-profit biorepository run by Public Health England.

In cases lacking explanatory protein-coding changes, researchers saw an uptick in de novo mutations in conserved, non-coding regulatory elements.

The researchers also found that genes located near these loci were differentially expressed in healthy versus diseased cartilage.

John Sulston Dies

Nobel-winner John Sulston, who also led the British effort to sequence the human genome, has died, BBC News reports.

Sequencing of typhoid fever outbreak samples in Pakistan indicates extensive drug resistance arose when a local multidrug resistance strain acquired a new plasmid.

At PAG, researchers from the Rockefeller University Vertebrate Genome Laboratory outlined sequencing and assembly strategies for phase 1 of the VGP G10K.

By sequencing Vibrio cholerae isolates from Africa and Latin America, investigators got a look at the lineages leading to outbreaks over several decades.

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Rady Children's Institute for Genomic Medicine and Deloitte are looking into the use of drones to transport samples for testing. 

Direct-to-consumer genetic testing firm 23andMe is laying off about 100 people.

Researchers from Northwestern University examined dust for antibiotic-resistance genes, New Scientist reports. 

In Science this week: researchers present a computational method for predicting cellular differentiation state from single-cell RNA sequencing data, and more.