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Wellcome Sanger Institute

At PAG, researchers from the Rockefeller University Vertebrate Genome Laboratory outlined sequencing and assembly strategies for phase 1 of the VGP G10K.

By sequencing Vibrio cholerae isolates from Africa and Latin America, investigators got a look at the lineages leading to outbreaks over several decades.

Using MRSA isolates from England, researchers uncovered hospital-specific, community-specific, and overlapping transmission clusters.

Such an atlas could enable investigators to understand how genetic variants impact disease risk, define drug toxicities, improve therapies, and advance regenerative medicine.

Investigators saw muted negative selection against mutations in genomic data for more than 7,600 tumors, while mining positive selection patterns for cancer driver clues.

Several studies describe a new Neanderthal genome, Neanderthal sequence effects on human traits, and ancient hunter-gatherer population social structure clues.

Data from hundreds of individuals suggest that the country's populations are genetically diverse, with a long history of genetic isolation and differentiation.

With sequence data for hundreds of advanced breast cancer samples, investigators identified genetic alterations shared with — and distinct from — those in primary tumors.

Investigators sequenced 3,700-year-old Canaanite genomes and compared them to present-day populations to explore the historical people's origin and fate.

Scientists from The Wellcome Trust Sanger Institute, Public Health England, and elsewhere sequenced the genomes of 209 MRSA isolates collected in Europe from 1960 to 1989.

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At a meeting this week, researchers and others discussed the regulatory oversight needed for germline genome editing.

The US Food and Drug Administration has asked questions about Myriad Genetics' GeneSight test, according to Bloomberg.

Researchers report that neutrophil extracellular traps appear to binds gallstones together, according to New Scientist.

In Science this week: approach to infer genotype-by-environment interaction from genetic variants associated with phenotypic variability, and more.