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Wellcome Sanger Institute

An analysis of more than 1,000 Neisseria gonorrhoeae genomes provided insights into antibiotic resistance patterns and related genomic features.

Independent research teams identified and sequenced hepatitis B strains going back thousands of years from samples in Europe, uncovering now-extinct lineages.

Using genome sequences for hundreds of ancient individuals, researchers have analyzed population dynamics and displacements around the Eurasian steppe.

While digging into the tumor-suppressive mechanism for an X-linked gene called UTX, researchers found a similar protective role for the Y chromosome gene UTY.

Saturation mutagenesis of the human malaria parasite Plasmodium falciparum identified almost 2,700 essential genes during the blood stage of infection.

Scientists have sequenced more than 2,700 distinct strains from the National Collection of Type Cultures, a non-profit biorepository run by Public Health England.

In cases lacking explanatory protein-coding changes, researchers saw an uptick in de novo mutations in conserved, non-coding regulatory elements.

The researchers also found that genes located near these loci were differentially expressed in healthy versus diseased cartilage.

John Sulston Dies

Nobel-winner John Sulston, who also led the British effort to sequence the human genome, has died, BBC News reports.

Sequencing of typhoid fever outbreak samples in Pakistan indicates extensive drug resistance arose when a local multidrug resistance strain acquired a new plasmid.

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At a meeting this week, researchers and others discussed the regulatory oversight needed for germline genome editing.

The US Food and Drug Administration has asked questions about Myriad Genetics' GeneSight test, according to Bloomberg.

Researchers report that neutrophil extracellular traps appear to binds gallstones together, according to New Scientist.

In Science this week: approach to infer genotype-by-environment interaction from genetic variants associated with phenotypic variability, and more.