Under the project, funded primarily with $15.7 million from the Wellcome Trust, the researchers plan to sequence the complete genomes of 4,000 people from two existing studies at low coverage, and the exomes of another 6,000 individuals with severe conditions believed to have a genetic component.
The institute's deputy director since 2007, Stratton is a team leader of Sanger's Cancer Genome Project, and a leader of the International Cancer Gene Consortium. He succeeds Allan Bradley, who in March stepped down after 10 years at the institute's helm.
At the Biology of Genomes meeting, Sanger Institute researcher Jeffrey Barrett argued that rare variants probably don't explain most signals detected in genome-wide association studies of common disease.
An international research team reported today that they have sequenced the genome of Trypanosoma brucei gambiense, the parasite that causes sleeping sickness in Africa, and started comparing it to a T. brucei reference genome.