The two papers indicate that whole-genome short-read sequencing technologies are becoming increasingly important for identifying cancer-causing genes that could eventually lead to better diagnosis and treatment.
An international research team has used sequencing approaches to identify, and begin characterizing, an antibiotic-resistant Salmonella enterica serotype Typhimurium bacterium behind a recent rash of invasive infections in sub-Saharan Africa.
The Wellcome Trust Sanger Institute for the first time released online its Annual Review, in which it disclosed that it plans to shift how it uses its sequencing capacity and upgrade its IT infrastructure.
Following three pilot projects, results of which are currently being analyzed, the project expects to sequence an additional 985 samples at 4x coverage by early 2010. One of the pilots, designed to test three second-generation sequencing technologies, showed that all three produce data that is suitable for the project.
Using SNP and expression microarrays, a team of researchers from Switzerland, the UK, and the US has uncovered cell type-specific differences in regulatory variant function within three different human cell types.