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Wellcome Sanger Institute

The European Nucleotide Archive consolidates the European Trace Archive, The Sequence Read Archive, and the Nucleotide Sequence Database into one EMBL resource.

Alex Bateman, Todd Johnson, Ilene Vogt

An international research team reported today that they have sequenced the genome of Trypanosoma brucei gambiense, the parasite that causes sleeping sickness in Africa, and started comparing it to a T. brucei reference genome.

Independent research groups have used array and sequencing-based approaches to catalog CNVs in three Asian populations and gain insights into CNV breakpoint patterns in three individuals.

Paired Ends: Mar 16, 2010


David Botstein, Francis Collins, Eric Lander, Leena Peltonen-Palotie, Carl Fuller, Fredrik Dahl

A pair of high-throughput RNA sequencing studies using Yoruban and European HapMap samples reveals the interplay between genetic variation and gene expression, splicing, and regulation.

Two independent research teams have used copy number and other genomic analyses to characterize cancer genomes.

New England Biolabs will supply the Wellcome Trust Sanger Institute with sample prep reagents suited for preparing next-generation sequencing samples and expression libraries.

The scientists said the project illustrates that thorough sequence analyses of cancer genomes can be done quickly, efficiently, and at a low cost outside of the large sequencing centers.

In a paper appearing online today in Science, researchers reported that they have come up with a high-throughput sequencing-based approach for teasing apart relationships between methicillin-resistant Staphylococcus aureus isolates from around the world and within a single health care facility.


The Washington Post reports that a Russian Academy of Sciences commission has led to the retraction of hundreds of scientific papers.

The Los Angeles Times' Daily Pilot reports the chief executive of Vantari Genetics has pleaded guilty in a kickback scheme.

News 4 Jax reports that a Florida bill to prevent life and long-term care insurers from using genetic information in their coverage decisions has easily passed one committee.

In Science this week: potentially pathogenic mutations found in hematopoietic stem cells from young healthy donors, and more.