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Wellcome Sanger Institute

The study highlights the potential of next-generation sequencing to identify variants that allow pathogenic bacteria to evade drugs, and could enable the development of new therapies.

New Products: Feb 1, 2011

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DNAStar's SeqMan NGen3, Halo Genomics' targeted resequencing kit, NuGen's Ovation Prokaryotic RNA-seq System, and the Sanger Institute's COSMIC version 51

A Wellcome Trust Sanger Institute-led team has sequenced and analyzed the genomes of more than 200 isolates from a drug-resistant Streptococcus pneumoniae lineage that emerged in Spain four decades ago.

By sequencing several cancer samples — and screening hundreds of cancer cell lines — researchers from the UK and US have garnered genetic evidence that cancer-related genomic rearrangements sometimes arise through large, lone mutation events.

The work identified 1,461 proteins tied to more than130 brain diseases, suggesting that synaptic proteins may figure more prominently in nervous system disorders than previously thought and could represent promising new targets for drug development.

Paired Ends: Nov 9, 2010

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David Swarbreck, George Church

The researchers now plan to move forward with low-coverage whole-genome sequencing and deep whole-exome sequencing of 2,500 individuals.

Researchers from the Wellcome Trust Sanger Institute system describe an insertional mutagenesis method that uses the PiggyBac transposon system to screen for cancer genes in mice.

New Products: Oct 5, 2010

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Integrated DNA Technologies's Fusion Primers and Library Molecular Identification Adaptor Oligos, Complete Genomics' CGA Tools, Bioo Scientific's AIR sample prep kits, NCBI's Database of Genomic Structural Variation, Omicsoft and GeneGo integrated software, and Wellcome Trust Sanger Institute's COSMIC

At a conference in Australia today, researchers from Illumina and the Wellcome Trust Sanger Institute announced that they have sequenced the Tasmanian devil genome, along with tumor genomes representing a contagious cancer decimating wild devil populations.

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The Washington Post reports on researchers' efforts to determine the effect of an increasingly common SARS-CoV-2 mutation.

Florida Politics reports Florida's law barring life, long-term care, and disability insurers from using genetic information in coverage decisions went into effect at the beginning of July.

A new analysis finds a link between popular media coverage of a scientific study and how often that paper is cited.

In Nature this week: CRISPR approaches to editing plant genomes, way to speed up DNA-PAINT, and more.