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Wellcome Sanger Institute

The pharma company will analyze genomic and clinical data from 2 million individuals over the next 10 years to drive drug development across its entire portfolio. 

By sequencing the genomes of more than 300 Shigella dysenteriae isolates, researchers identified lineages involved in worldwide outbreaks prior to WWI.

Researchers used the computational method to identify T cell clonotypes in a mouse Salmonella infection model.

Investigators looked at potential health impacts for the rare, homozygous loss-of-function mutations they detected in 3,200 British-Pakistani individuals.

Sequences from Chlamydia trachomatis strains in northern Australia suggest trachoma infections in the eye may be caused by small changes to urogenital strains.

The conference, held at The Wellcome Trust Sanger Institute, highlighted CRISPR research from European and private sector scientists in particular.

Along with breast, ovarian, and pancreatic cancers, the "signature 3" mutation pattern was detected in around 10 percent of sequenced gastric tumors.

The arrayed lentiviral CRISPR/Cas9 guide RNA libraries provide the tools to knock out every known human or mouse protein-coding gene.

Researchers sequenced the whole genomes of nearly 4,000 individuals and the exomes of nearly 6,000 individuals, and created a genotype reference panel.

In a study published in PNAS, the researchers found that the bacteria has split into three distinct species and is developing multiple clones that are highly virulent or drug resistant.

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Nature News reports that genomics is being applied to trace and try to prevent additional COVID-19 waves.

Rady's Children Hospital and San Diego County are teaming up to test pediatric patients and their families for COVID-19 to gauge the spread of the virus locally, according to the San Diego Union-Tribune.

Wildlife managers aim to boost the genetic diversity of Mexican gray wolves by placing captive-born foster pups into packs with similarly aged wild pups, the Mercury News reports.

In Science this week: Genetic Probability tool identifies likely diagnoses in 45 percent of inflammatory arthritis cases, and more.