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Investigators uncovered 33 hotspots of large tandem duplications among breast cancer cases that affected cancer susceptibility genes and super-enhancers.
The researchers said their one-step, inducible, multiplex gene knockdown and gene knockout platforms can be used in many differentiated cell types.
The Bridget Ogilvie Building will house sequencing facilities, and the Biodata Innovation Centre will host genomic startups.
Two new studies are exploring genomic features and population variation in the river blindness-causing parasite Onchocerca volvulus.
A sequencing study suggests multidrug-resistant Mycobacterium abscessus bacteria are often passed between people, not acquired from the environment.
Two independent research teams linked plasmepsin 2 and plasmepsin 3 gene amplifications to piperaquine resistance.
By analyzing mutations in tumors from a broad swath of tobacco smoke-related cancer types, investigators identified more than two-dozen mutational signatures.
The researchers will use single-cell genomics and other approaches to generate information that could ultimately be used to diagnose, monitor, and treat disease.
An international team analyzed the genomes of 65 wild-born chimpanzees and 10 bonobos to uncover evidence of gene flow.
Using sequence data for more than 1,800 Salmonella enterica serovar Typhi isolates, researchers identified 68 SNPs to trace the bug to its geographical source.
A study of families explores how children transmit SARS-CoV-2, according to the Associated Press.
US Agricultural Research Service scientists have sequenced the genome of the Asian giant hornet.
According to the Economist, pooled testing for COVID-19 could help alleviate strains on testing labs.
In Science this week: MIT researchers outline approach dubbed translatable components regression to predict treatment response among IBD patients.