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Wellcome Sanger Institute

A nationwide, multi-agency effort to sequence the virus causing COVID-19 is a logistical nightmare, but experts say the UK is well situated to succeed.

Following its Path

The UK is launching a research consortium to sequence SARS-CoV-2 samples from patients.

The consortium, which spans more than a dozen UK cities, will sequence patient samples to understand the spread and evolution of the novel coronavirus.

In Science this week: sequencing of diverse human genomes gives insight into genetic variation and population history, commentary on data sharing, and more.

Researchers from the Human Genome Diversity Project discovered common genetic variation that is largely restricted to regions of Africa, Oceania, and the Americas.

Bioinformatics firm Next Gen Diagnostics will integrate Fluidigm's Juno microfluidic sample prep system into its workflow for pathogen whole-genome sequencing.

In Science this week: comprehensive cellular map of the human thymus, evidence of admixture between the ancestors of Neanderthals and Denisovan and a 'superarchaic' population.

Members of a large, international consortium tapped into whole-genome sequences from nearly 2,700 tumors to explore coding and non-coding variants contributing to cancer.

In Nature this week: sequencing analysis finds some cells in the lungs of former smokers have mutational burdens that were equivalent to those of never-smokers, and more.

Researchers found that some cells from former smokers had mutational patterns more similar to those from never-smokers, suggesting that quitting at any age can be beneficial.

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Kelvin Droegemeier, the director of the White House Office of Science and Technology Policy, is the new acting director of the US National Science Foundation.

An opinion piece at the Guardian discusses the state of SARS-CoV-2 testing in the UK.

Wired reports the University of California, Berkeley's Innovative Genomics Institute has transformed itself into a diagnostic lab to run SARS-CoV-2 tests.

In Nature this week: direct-capture Perturb-seq approach for combinatorial single-cell CRISPR screens, potential uses of genome-editing in breeding crops, and more.