Wellcome Sanger Institute SARS-CoV-2 Genomes Reveal Dynamics of England's Alpha, Delta Variant Surges Analyzing SARS-CoV-2 isolates circulating in England over 10 months up to June 2021, researchers saw a series of epidemics dominated by distinct viral lineages. Chronic Liver Disease Genome Sequences Point to Recurrent Mutations in Metabolic Genes Metabolic pathway mutations turned up across individuals and liver clones in non-alcoholic fatty liver disease or alcohol-related liver disease patients. Individuals With Polymerase Defects Have Increased Somatic Mutations, But Not Increased Aging The findings suggested to the researchers that the increase in somatic mutations observed as people get older may not be the sole cause of aging-related diseases. Blood, Immune Cell Formation in Fetal Bone Marrow Detailed in Cell Atlas Effort The researchers found that blood and immune cells quickly diversify within fetal bone marrow, but that there are differences in Down syndrome samples. Genetic Analyses Trace How Mutations Accumulate in Cells of the Human Body Over Time Four new studies have followed somatic mutations that arise in human cells to unravel cell lineages and examine the development of cancer. Aug 5, 2021 Genome, Metagenomic Sequence Data Highlight Microbe Adaptations to Human Guts Aug 4, 2021 Middle Eastern Genomes Provide Look at Genetic Variation, Population Histories Jul 6, 2021 MIT-Led Team Develops Genomics Platform to Support Heart Disease Treatment Decisions Premium Apr 16, 2021 Autoimmune Disease Risk Tied to Genetic Variation in Transcription Factor Binding Mar 4, 2021 At AGBT, Two Labs Share SARS-CoV-2 Genomic Surveillance Experience Premium Feb 19, 2021 Qiagen Launches 'Digital Partner' Program to Expand Bioinformatics Reach Feb 18, 2021 Study Reveals Wide Range of Viruses in Human Gut Bacteria Feb 16, 2021 Two Studies Uncover Risk Loci for Age-Associated Neurodegenerative Disorders Feb 5, 2021 Childhood Cancer Study Reveals Pan-Neuroblastoma Cell State Feb 4, 2021 Qiagen Takes Over Commercial Sales of Sanger's COSMIC Database Premium Dec 8, 2020 Single-Cell Transcriptome Study Links Gut Development, Pediatric Crohn's Disease Nov 23, 2020 Broad Institute DepMap Project Could Lead to Development of New Cancer Drugs Premium Oct 14, 2020 Developmental Disorder Study Identifies 28 Novel Disease Genes Oct 8, 2020 Genomic Data Helps Explain Yaws Re-emergence, Antibiotic Resistance in Papua New Guinea Oct 1, 2020 Genomic Study of Argentinian Cholera Outbreak Finds Differences Between Endemic, Epidemic Bacteria Oct 1, 2020 Cancer Clues Gleaned from Somatic Mutation Patterns in Normal Bladders Sep 24, 2020 Single-Cell Transcriptome Atlas of the Human Heart Highlights Heterogeneity Sep 24, 2020 Antibiotic Resistance Spread in Europe Informed by Bacterial Plasmid Sequencing Sep 17, 2020 Willingness to Donate DNA to Research Is Low, Global Survey Finds Sep 16, 2020 Viking Age Human Migrations Untangled Through Ancient DNA Analysis Load More Breaking News New Approach Identifies Candidate Causal Variants for Neuropsychiatric, Neurodevelopmental Conditions People in the News: Baylor's Thomas Caskey Dies; New Appointments at UK Biobank, CS Genetics, More In Brief This Week: Pathogenomix, Uniogen, Genetic Technologies, DnaNudge, Gravity Diagnostics, More New Products Posted to GenomeWeb: Biodesix, Curio Genomics, Akoya Biosciences, More NIH Earmarks $170M for All of Us Program's Personalized Nutrition Study Taiwanese Firm's IP Asserted in Suit Against Pacific Biosciences Found Partially Unpatentable The Scan Omicron's Sewage Path The New York Times writes that testing sewage is helping public health officials track Omicron. IBM Sells Part of Watson Health The Wall Street Journal reports IBM is selling part of its Watson Health business to an investment firm. Identifying the Right Whales The Boston Globe writes that genetic testing has helped identify North American right whales and find that weaning can take place earlier than thought. Science Papers on Approach to Quickly Sort Single Cells, Alternative Splicing in Cancer In Science this week: high-speed sorting of single cells using fluorescence imaging, and more.