Wellcome Sanger Institute
SARS-CoV-2 Genomes Reveal Dynamics of England's Alpha, Delta Variant Surges
Analyzing SARS-CoV-2 isolates circulating in England over 10 months up to June 2021, researchers saw a series of epidemics dominated by distinct viral lineages.
Chronic Liver Disease Genome Sequences Point to Recurrent Mutations in Metabolic Genes
Metabolic pathway mutations turned up across individuals and liver clones in non-alcoholic fatty liver disease or alcohol-related liver disease patients.
Individuals With Polymerase Defects Have Increased Somatic Mutations, But Not Increased Aging
The findings suggested to the researchers that the increase in somatic mutations observed as people get older may not be the sole cause of aging-related diseases.
Blood, Immune Cell Formation in Fetal Bone Marrow Detailed in Cell Atlas Effort
The researchers found that blood and immune cells quickly diversify within fetal bone marrow, but that there are differences in Down syndrome samples.
Genetic Analyses Trace How Mutations Accumulate in Cells of the Human Body Over Time
Four new studies have followed somatic mutations that arise in human cells to unravel cell lineages and examine the development of cancer.