Wellcome Sanger Institute Genetic Analyses Trace How Mutations Accumulate in Cells of the Human Body Over Time Four new studies have followed somatic mutations that arise in human cells to unravel cell lineages and examine the development of cancer. Genome, Metagenomic Sequence Data Highlight Microbe Adaptations to Human Guts In bacteria from the Firmicutes phylum, investigators saw several adaptations to the human gut suspected of influencing microbial abundance and their ability to spread between individuals. Middle Eastern Genomes Provide Look at Genetic Variation, Population Histories With phased genome sequences for 137 individuals from eight Middle Eastern populations, investigators found millions of new genetic variants and retraced past population interactions. MIT-Led Team Develops Genomics Platform to Support Heart Disease Treatment Decisions Premium The platform is already being used in drug development and could eventually be harnessed to guide therapy selection in at-risk patients. Nucleic Acids Research Papers on DeepFun, gutSMASH, COVID-19 Data Portal In Nucleic Acids Research this week: deep learning approach to gauge consequence of non-coding variants, way to predict primary metabolic gene clusters, and more. Mar 4, 2021 At AGBT, Two Labs Share SARS-CoV-2 Genomic Surveillance Experience Premium Feb 19, 2021 Qiagen Launches 'Digital Partner' Program to Expand Bioinformatics Reach Feb 18, 2021 Study Reveals Wide Range of Viruses in Human Gut Bacteria Feb 16, 2021 Two Studies Uncover Risk Loci for Age-Associated Neurodegenerative Disorders Feb 5, 2021 Childhood Cancer Study Reveals Pan-Neuroblastoma Cell State Feb 4, 2021 Qiagen Takes Over Commercial Sales of Sanger's COSMIC Database Premium Dec 8, 2020 Single-Cell Transcriptome Study Links Gut Development, Pediatric Crohn's Disease Nov 23, 2020 Broad Institute DepMap Project Could Lead to Development of New Cancer Drugs Premium Oct 14, 2020 Developmental Disorder Study Identifies 28 Novel Disease Genes Oct 8, 2020 Genomic Data Helps Explain Yaws Re-emergence, Antibiotic Resistance in Papua New Guinea Oct 1, 2020 Genomic Study of Argentinian Cholera Outbreak Finds Differences Between Endemic, Epidemic Bacteria Oct 1, 2020 Cancer Clues Gleaned from Somatic Mutation Patterns in Normal Bladders Sep 24, 2020 Single-Cell Transcriptome Atlas of the Human Heart Highlights Heterogeneity Sep 24, 2020 Antibiotic Resistance Spread in Europe Informed by Bacterial Plasmid Sequencing Sep 17, 2020 Willingness to Donate DNA to Research Is Low, Global Survey Finds Sep 16, 2020 Viking Age Human Migrations Untangled Through Ancient DNA Analysis Sep 3, 2020 Blood Cell Traits Linked to Individual Loci, Polygenic Contributors in International Studies Jul 21, 2020 Inflammatory Bowel Disease Study Points to Role For Somatic Colon Mutations Jun 11, 2020 Analysis of Diverse Set of Human Genomes Uncovers Novel Structural Variation May 28, 2020 Ancient DNA Studies in the Near East Detail Complex, Interconnected Population Histories Load More Breaking News Beckman Coulter, Invitae Partner to Develop NGS Library Prep Applications Sick Infants Profiled with WGS See Better Diagnosis, More Care Changes UC Santa Cruz Center for Live Cell Genomics Wins $13.5M NIH Grant Genetron Health, Impact Therapeutics Partner for Anti-Cancer Drug, CDx Development Canaccord Genuity Initiates Coverage of Pacific Biosciences With Buy Rating Alternative Genetic Counseling Approach Leads to Higher Patient Satisfaction, Study Suggests The Scan Highly Similar Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News. Gain of Oversight According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research. Lasker for mRNA Vaccine Work The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.