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Wellcome Sanger Institute

Autoimmune Disease Risk Tied to Genetic Variation in Transcription Factor Binding

A new study has found that variants affecting PU.1 transcription factor binding are also linked to susceptibly to autoimmune diseases.

At AGBT, Two Labs Share SARS-CoV-2 Genomic Surveillance Experience
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The Wellcome Sanger Institute and the BC Centre for Disease Control Public Health Lab have been using viral sequencing to follow the spread of variants of concern.

Qiagen Launches 'Digital Partner' Program to Expand Bioinformatics Reach

Initial partners in the program include Thermo Fisher Scientific, GNS Healthcare, DNAnexus, Personal Genome Diagnostics, and the Wellcome Sanger Institute.

Study Reveals Wide Range of Viruses in Human Gut Bacteria

Using metagenomic and bacterial reference genome sequences, researchers assembled a collection of bacteriophage genomes from individuals around the world.

Two Studies Uncover Risk Loci for Age-Associated Neurodegenerative Disorders

One study found new risk loci for Alzheimer's disease, while the other focused on Lewy body dementia risk.

Feb 5, 2021

Childhood Cancer Study Reveals Pan-Neuroblastoma Cell State

Feb 4, 2021

Qiagen Takes Over Commercial Sales of Sanger's COSMIC Database
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Dec 8, 2020

Single-Cell Transcriptome Study Links Gut Development, Pediatric Crohn's Disease

Nov 23, 2020

Broad Institute DepMap Project Could Lead to Development of New Cancer Drugs
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Oct 14, 2020

Developmental Disorder Study Identifies 28 Novel Disease Genes

Oct 8, 2020

Genomic Data Helps Explain Yaws Re-emergence, Antibiotic Resistance in Papua New Guinea

Oct 1, 2020

Genomic Study of Argentinian Cholera Outbreak Finds Differences Between Endemic, Epidemic Bacteria

Oct 1, 2020

Cancer Clues Gleaned from Somatic Mutation Patterns in Normal Bladders

Sep 24, 2020

Single-Cell Transcriptome Atlas of the Human Heart Highlights Heterogeneity

Sep 24, 2020

Antibiotic Resistance Spread in Europe Informed by Bacterial Plasmid Sequencing

Sep 17, 2020

Willingness to Donate DNA to Research Is Low, Global Survey Finds

Sep 16, 2020

Viking Age Human Migrations Untangled Through Ancient DNA Analysis

Sep 3, 2020

Blood Cell Traits Linked to Individual Loci, Polygenic Contributors in International Studies

Jul 21, 2020

Inflammatory Bowel Disease Study Points to Role For Somatic Colon Mutations

Jun 11, 2020

Analysis of Diverse Set of Human Genomes Uncovers Novel Structural Variation

May 28, 2020

Ancient DNA Studies in the Near East Detail Complex, Interconnected Population Histories

May 6, 2020

Chan Zuckerberg Initiative Grants $750K to COVID-19 Studies Using Single-Cell Methods

Apr 23, 2020

Coronavirus Entry Genes Highly Expressed in Two Nasal Epithelial Cell Types

Apr 22, 2020

Normal Endometrial Glands Harbor Cancer-Associated Mutations, Study Finds

Mar 25, 2020

UK COVID-19 Sequencing Consortium to Reveal Viral Spread, Evolution

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The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.