Wellcome Sanger Institute

The project represents the UK portion of a broader initiative to sequence the genomes of all 1.5 million known animals, plants, protozoa, and fungi.

B-cell receptor sequencing revealed lower-than-usual memory immune cell activity and more in unvaccinated children after measles virus infection.

Researchers documented population structure, ancestry patterns, trait associations, and more with variants found in the genomes of more than 6,400 Ugandans.

Although normal tissues with somatic mutations did not necessarily progress to cancer, researchers saw a jump in mutational burden in samples associated with cancer or cirrhosis.

Thousands of parent-child exomes helped researchers identify apparently causative mobile element insertions in a handful of children with developmental disorders.

Congenica has also integrated the Wellcome Sanger Institute's DECIPHER web-based genomic variant database into its clinical decision support product.

Researchers from Wellcome Sanger Institute and elsewhere found that the immune landscape of the kidney is zoned to counter dominant immunological challenges.

Using 350 human genomes from different populations, the two centers plan to develop a multi-genome reference sequence that is as complete as possible.