Wellcome Sanger Institute
Developmental Disorder Study Reveals Recessive Genetic Contributors in Diverse Populations
Researchers explored the genetics of autosomal recessive developmental disorders in two large, diverse cohorts, linking some 84 percent of cases to known disease genes.
Whole-Genome Sequencing Approach Enables Simultaneous Surveillance of Hospital-Associated Pathogens
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Described in a proof-of-concept study, the method demonstrated the potential utility of pan-pathogen sequencing for monitoring hospital-associated infections.
Study Points to Microbial Pioneers Behind Infant Gut Microbiome Assembly
Researchers identified three early gut microbiome community states and corresponding pioneer microbes with metagenomic data from the UK Baby Biome Study.
Blood Plasma Extracellular Vesicles Provide Window Into Cerebral Malaria in Affected Children
Extracellular vesicles in the blood were shown to contain clues about gene expression shifts in the brains of children with retinopathy-positive or -negative cerebral malaria.
Pneumococcus Evolution, Spread Profiled With Genome Sequences, Mobile Phone Data
By combining mobility and genomic data, researchers traced Streptococcus pneumoniae transmission in South Africa, and evaluated vaccine effects on fitness.