Wayne State University

This Week in PLOS

In PLOS this week: transcription levels linked to uracil mutations, transcriptomic analysis of medicinal leech, and more.

Variants in CETP-inhibitor and statin target genes helped investigators untangle complex ties between low-density lipoprotein levels and cardiovascular events.

Investigators identified candidate protein markers from aptamer-based proteomic profiles of samples from women with or without late-onset preeclampsia.

Several academic and commercial groups are developing clinical cell-based noninvasive prenatal tests, which could eventually compete with current cell-free NIPTs.

The team has been monitoring changes in host gene expression patterns due to different types of infections, and hopes to develop a diagnostic test.

The grant, worth $1.4 million in its first year, will be used to develop a panel of RNA expression signatures that can diagnose infections in febrile infants.

The five-year grant will support optimizing the use of polymyxin B to treat Gram-negative bacterial infections and identify protein biomarkers of drug-associated toxicity.

Scientists from Wayne State University have found a set of 648 sperm RNA elements that could predict male fertility and help inform couples trying to conceive.

Three collaborators will further explore the clinical usefulness of a TAA panel in early cancer detection and measuring response to cancer immunotherapy.

NEW YORK (GenomeWeb) – A team from Wayne State University and Michigan's Isle Royale National Park have demonstrated the feasibility of using Ion Torrent sequencing to assess microbial community samples being introduced into the environment.

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A University of California, Los Angeles-led team has found turning off the CCR5 gene could improve recovery after a stroke, according to Scientific American.

South Dakota lawmakers are to weigh a bill aimed at teaching the strengths and weaknesses of scientific concepts, the Associated Press and KEVN-Black Hills Fox report.

In Science this week: the synthetic genetic system hachimoji, and more.

Thermo Fisher Scientific says it will no longer sell machines in China's Xinjiang region, according to the Wall Street Journal.