In PLOS this week: transcription levels linked to uracil mutations, transcriptomic analysis of medicinal leech, and more.
Variants in CETP-inhibitor and statin target genes helped investigators untangle complex ties between low-density lipoprotein levels and cardiovascular events.
Investigators identified candidate protein markers from aptamer-based proteomic profiles of samples from women with or without late-onset preeclampsia.
Several academic and commercial groups are developing clinical cell-based noninvasive prenatal tests, which could eventually compete with current cell-free NIPTs.
The team has been monitoring changes in host gene expression patterns due to different types of infections, and hopes to develop a diagnostic test.
The grant, worth $1.4 million in its first year, will be used to develop a panel of RNA expression signatures that can diagnose infections in febrile infants.
The five-year grant will support optimizing the use of polymyxin B to treat Gram-negative bacterial infections and identify protein biomarkers of drug-associated toxicity.
Scientists from Wayne State University have found a set of 648 sperm RNA elements that could predict male fertility and help inform couples trying to conceive.
Three collaborators will further explore the clinical usefulness of a TAA panel in early cancer detection and measuring response to cancer immunotherapy.
NEW YORK (GenomeWeb) – A team from Wayne State University and Michigan's Isle Royale National Park have demonstrated the feasibility of using Ion Torrent sequencing to assess microbial community samples being introduced into the environment.
The American Prospect writes that the pilot program to test the DNA of migrants could lead to more family separations.
An international commission is to develop a report on how researchers, clinicians, and regulators should evaluate the clinical applications of human germline genome editing.
The US Department of Agriculture presents a new blueprint for animal genomic research.
In Genome Research this week: repetitive element deletion linked to altered methylation and more in form of muscular dystrophy; human contamination in draft bacterial and archaeal genomes; and more.