Washington University

The university has renamed its genomics center, specializing in the gut microbiome, the Edison Family Center for Genome Sciences and Systems Biology.

Results from up to eight stages of mouse or human retina development highlight the importance of histone modifications and other epigenetic shifts during differentiation.

Researchers reported that structural variants also tend to have larger effect sizes than single-nucleotide variants or insertions and deletions.

The technology, called Tunr, involves targeting translation elongation by introducing consecutive adenosine nucleotides into a gene coding sequence of interest.

Protein patterns in patient-derived xenografts sometimes pointed to different alterations than those predicted from somatic mutation and expression data.

As PierianDx grows, two customers weighed in on their experiences with the core product, the Clinical Genomicist Workspace, and its NGS-related services.

The centers are using the standardized pipeline to help streamline data sharing and data analysis to achieve their larger research goals.

The funding will, in part, support efforts to expand the project's catalog of functional elements and understand their roles in different contexts.

The Familial Mutation

Researchers are studying people with familial early-onset Alzheimer's disease to gain insight into the disease, NPR reports.

This Week in PNAS

In PNAS this week: genetic variants linked to response to food ads, effects of MECP2 mutations in Rett syndrome, and more.

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The partially reinstated US travel ban leaves space for uncertainty for researchers, Nature News says.

Researchers find a number of traits differ by sex and could affect mouse model studies, according to Reuters.

Tweaking the skin microbiome could help address some skin conditions, the New York Times reports.

In PNAS this week: DNA methylation profiles of tumor tissue, gene dynamics in prokaryotes, and more.