Washington University

Results from a recent study suggest that considering nearby variants can improve the accuracy of neoantigen selection, resulting in better personalized vaccines for patients.

GWAS summary statistics data led to three main loci with ties to both Alzheimer's and cardiovascular disease, with additional enrichment at lipid-related sites.

The solution uses machine learning to pare down somatic variant lists, simplifying the task of manually reviewing the output of sequence analysis pipelines.

Individuals with higher-than-usual mutant allele frequencies after stem cell transplantation were prone to disease progression and reduced progression-free survival.

This Week in Nature

In Nature this week: new susceptibility loci for diverticular disease, and more.

With targeted gene sequencing data from a large set of archived tumor samples, researchers identified somatic mutations coinciding with better or worse overall survival.

This Week in PLOS

In PLOS this week: ties between complex traits and autozygosity, salt tolerance markers in the Chinese rose, and more.

This Week in Cell

In Cell this week: structural variants affecting regulatory loci in prostate cancer, immune features in the breast cancer microenvironment, and more.

The institutes will explore the use of Inivata's liquid biopsy platform to analyze ctDNA to measure minimal residual disease in NSCLC patients.

This Week in Nature

In Nature this week: genome-wide CRISPR-Cas9 screen finds key cell surface receptor used by the chikungunya virus, and more.

Pages

A genomic analysis of modern and ancient maize reveals a complicated domestication history, according to Reuters.

CNBC reports that half of academic researchers leave after about five years.

In PLOS this week: MYRF variant linked to congenital diaphragmatic hernia, analysis of the "dragon's blood" red resin produced by traditional medicine plants, and more.

Researchers have used genetic analysis to confirm a new type of salamander, the New York Times reports.