Washington University

This Week in Science

In Science this week: wild tetraploid wheat genome, and more.

The university has renamed its genomics center, specializing in the gut microbiome, the Edison Family Center for Genome Sciences and Systems Biology.

Results from up to eight stages of mouse or human retina development highlight the importance of histone modifications and other epigenetic shifts during differentiation.

Researchers reported that structural variants also tend to have larger effect sizes than single-nucleotide variants or insertions and deletions.

The technology, called Tunr, involves targeting translation elongation by introducing consecutive adenosine nucleotides into a gene coding sequence of interest.

Protein patterns in patient-derived xenografts sometimes pointed to different alterations than those predicted from somatic mutation and expression data.

As PierianDx grows, two customers weighed in on their experiences with the core product, the Clinical Genomicist Workspace, and its NGS-related services.

The centers are using the standardized pipeline to help streamline data sharing and data analysis to achieve their larger research goals.

The funding will, in part, support efforts to expand the project's catalog of functional elements and understand their roles in different contexts.

The Familial Mutation

Researchers are studying people with familial early-onset Alzheimer's disease to gain insight into the disease, NPR reports.

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A former Synthetic Genomics attorney alleges that the firm discriminated against her and other female employees, according to the San Diego Union-Tribune.

Due to privacy and lab certification questions, the planned giveaway of Orig3n testing kits at a Baltimore Ravens game was suspended.

Alnylam reports positive results from its phase 3 clinical trial of an RNAi-based drug, according to Stat News.

In Cell this week: adult mesenchymal cell populations in mouse lung, genetic diversity in HPV16 and cancer risk protection, and more.