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Vanderbilt

Prostate Cancer Polygenic Score Does Not Improve High-Grade Disease Prediction Over Clinical Factors

Researchers found that adding genetic risk score data did not improve their ability to predict aggressive prostate cancer cases over conventional risk stratification approaches.

Illumina, Nashville Biosciences Ink WGS Agreement With Amgen for African American Cohort

As part of the agreement, Amgen subsidiary DeCode Genetics will perform WGS on 35,000 DNA samples from VUMC's biobank using Illumina platforms.

CardioVar Consortium Wins $8.2M From NHLBI to Map Heart Disease Variants, Functional Effects

The investigators hope to eventually create a decision support resource with utility for physicians evaluating genetic test results in heart disease patients.

Variants Linked to Microbiome Traits Implicated in Range of Traits, Conditions

A phenome-wide association study focused on microbiome-associated variants led to conditions ranging from skin disease to diabetes, heart disease, or multiple sclerosis.

 

Massive Bio Launches Plan to Enroll 100K Cancer Patients Into Clinical Trials
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The bioinformatics firm hopes its AI and "NASA-style" command center will make it easier to get cancer patients into NGS labs and improve trial matching.

Nov 17, 2021

Identifying Individuals in Genomic Datasets From Headshots Harder Than Expected

Oct 27, 2021

Polygenic Risk Scores Edge Toward Clinic, Though Disease Prediction Utility Questions Linger
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Jun 3, 2021

EHR-Based Model Predicts Patients Who May Benefit from Genetic Testing for Rare Disease

May 24, 2021

AACR Presentations Highlight Power of Large Tumor Atlases in Studies of Cancer Progression
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Apr 27, 2021

Syntegra Teams With Vanderbilt's Nashville Biosciences on Biobank Data Analysis for Drug R&D

Dec 9, 2020

Appendiceal Cancer Sequences Suggest Distinct Mutation Patterns in Early-, Late-Onset Cases

Nov 23, 2020

Twist Bioscience Plots Continued Growth With NGS Product Push Into Ag-Bio, Cancer Dx
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Nov 5, 2020

Jackson Laboratory Wins $3.4M NHGRI Grant to Study Workplace Genomic Testing

Aug 4, 2020

Genuity Science Gains Access to BioVU With Nashville Biosciences Deal

Jul 30, 2020

Double-Barcoded Single-Cell Library Prep Solves Index-Hopping Issues, Lowers Sequencing Costs
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Jul 28, 2020

Neanderthals Reintroduced Alleles from Common Ancestor to Modern Humans

Jul 22, 2020

Risk-Assessment Phase of eMERGE Looks to Diversify Polygenic Risk Scoring
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Jul 1, 2020

NIH Allocates $75M to Create eMERGE Risk Assessment Network

Jun 24, 2020

Two Polycystic Ovary Syndrome Subtypes Emerge From Phenotypic Clustering Analysis
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May 21, 2020

Genomic, Synthetic Bio Platforms Power COVID-19 Antibody Discovery at Vanderbilt Lab
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Apr 24, 2020

National Genomics Programs in UK, US Change Data Storage Calculations
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Apr 8, 2020

Pacific Biosciences Shares Spike on SARS-CoV-2 Research Initiatives

Mar 6, 2020

PMI Biopharma, Nashville Biosciences Form Drug Development Services Alliance

Feb 18, 2020

Polygenic Risk Score Studies Suggest Conventional Heart Disease Prediction Methods Still Preferable

Nov 20, 2019

Lower Cutoff Score for Oncotype DX Test May Be Needed for Male Breast Cancer Patients

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The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.