UT Southwestern Most Genetic Counselors Encounter Discrepant Variant Classifications, Must Work Out Interpretations Premium While neither common nor rare, discrepant variant classification can affect the management of patient care, and there are efforts to improve interpretations. New Data Underscores Volatility of Variant Classification, Highlights Need for Regular Reanalysis A review of Myriad Genetics' results over 10 years revealed that a significant proportion of variant calls were reclassified at some point. Rhabdomyosarcoma Genes Revealed by Statistical Analysis of Gene Expression, CNV Data The approach, published this week in Cell Reports, could be used more generally to discover disease genes in other cancer types. Variant Reclassification Common, Causes Range of Emotions Among Patients Two speakers at the National Society of Genetic Counselors annual meeting discussed how often genetic variants are reclassified and how that affects patients. Biocept, UT Southwestern Partner for ALK Liquid Biopsy Study Investigators will use Biocept's liquid biopsy tests to detect ALK rearrangements both at baseline and to monitor treatment response and resistance mechanisms. Mar 7, 2017 Exosome Surface Markers May Enable Cancer-Specific Dx Tests Premium Feb 27, 2017 Gene-Editing Startup Exonics Therapeutics Receives $5M From CureDuchenne Ventures Jan 30, 2017 Parent Project Muscular Dystrophy Funds $250K CRISPR Grant for UT-Southwestern Jul 14, 2016 U of Texas Southwestern Medical Center Licenses Exosome Tech to Peregrine Pharmaceuticals Jan 18, 2016 UT Southwestern Team Finds ncRNA-Encoded Peptide Involved in Heart Contraction May 26, 2015 CPRIT Awards $5.6M to UT Southwestern Medical Center Bioinformatics Core Facility May 18, 2015 UTSW Medical Center Receives $5M Gift to Create Depression Research Center Aug 14, 2014 Using Genome Editing Approach, Researchers Prevent Duchenne Muscular Dystrophy in Mouse Model Dec 19, 2013 Genomics in the Journals: Dec 19, 2013 Dec 11, 2013 With $3.2M, DioGenix Planning Prospective Trial Completion in 2014, CLIA Bid for MS Sequencing Test Premium Dec 5, 2013 DioGenix Raises $3.2M to Support Multiple Sclerosis Test Development Oct 8, 2013 Study Links Two Gene Variants, One Pathway to Eating Disorder Risk Jan 28, 2013 MolecularMD Licenses LKB1 Marker for Lung Cancer Assay Development Jan 2, 2013 With $1.5M in New Financing, DioGenix Starts Prospective Trial of Targeted Sequencing-based MS Test Premium Nov 8, 2011 Texas Grants Fund Cancer Sequencing, 'Omics Projects Sep 8, 2011 Miragen, UT Southwestern Show miR-208 Inhibition Improves Survival in Rodent Heart-Failure Models Premium Jul 28, 2011 Miragen, UT Southwestern Team Publishes Data Linking miR-15 to Cardiomyogenesis Premium Sep 17, 2010 TARC Team Uses RBM's DiscoveryMAP Platform to Develop Alzheimer's Protein-Biomarker Test Premium Mar 10, 2010 WaferGen Names Early-Access Customers for SmartChip Mar 10, 2010 Wafergen Names Early-Access Customers, Gets CE Mark for SmartChip PCR System Premium Load More Breaking News In Ongoing False Advertising Suit, Judge Allows Natera Counterclaims Against Guardant Health Centogene Strikes Rare Disease Target Discovery Deal With Insilico Medicine Dilated Cardiomyopathy Gene Mutations Point to Possible Therapeutic Strategy Ginkgo Bioworks Acquires Massachusetts COVID-19 Testing Firm Mainz Biomed Taps DCN Dx to Aid European Study of Enhanced ColoAlert Assay Parse Biosciences Partners With Research Instruments for Southeast Asia Distribution The Scan Transplant Tests Edited Pig Kidneys The Associated Press reports a University of Alabama-Birmingham team transplanted genetically modified pig kidneys into a brain-dead human patient. UK Changes Some Gene-Edited Crop Rules A new law may enable gene-edited crops to be sold in the UK within about five years, New Scientist says. Pill Works Against Omicron in Lab Pfizer's antiviral pill to treat SARS-CoV-2 appears to work against the Omicron variant, the Wall Street Journal reports. Nature Papers Find Genetic Risk Factor for Smell, Taste Loss in COVID-19; Analyze TB Granulomas In Nature this week: genome-wide association study find locus linked to the risk COVID-19 patients losing their sense of taste or smell, and more.