By screening more than 1,500 drugs against patient-derived glioblastoma cells, researchers tracked down tumor alterations with apparent ties to proteasome inhibitor response.
Investigators analyzed the expression of protein-coding genes in 18 blood immune cell populations, comparing the expression profiles with those in other cell and tissue types.
In PNAS this week: signals of natural selection among Indigenous populations of North America, population and social structures of several European Stone Age burial sites, and more.
Modern Grauer's gorillas have experienced a decline in genetic diversity, more so than mountain gorillas, even as both have experienced population decline.
A new analysis found kidney disease-related pathogenic or likely pathogenic variants in exomes for roughly 9 percent of individuals with chronic kidney disease.
