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Aug 10, 2015

Recurrent Mutations Point to Signaling Processes Behind Some Cutaneous T Cell Lymphoma Cases

Researchers characterized mutation patterns in mycosis fungoides and Sézary syndrome using a combination of exome sequencing and targeted sequencing.

Aug 03, 2015

Might Lead to a Couple of Snags

Bioethicists weigh the idea of charging patients to take part in clinical research, coming down against the approach.

Apr 07, 2015

Team Begins Defining Cancer Risk Patterns for Distinct BRCA1, BRCA2 Mutations

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With data for almost 31,500 women, researchers uncovered regions of BRCA1 and BRCA2 where mutations most closely correlated with breast or ovarian cancer diagnoses.

Jan 02, 2015

Using Novel Sequencing Method, Researchers Measure Global RNA-Protein Binding in Plant Nuclei

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The technique, protein interaction profile sequencing, can capture both the pattern of protein-RNA binding sites and the larger structure of nuclear or other transcripts.

Dec 18, 2014

UPenn, UGA Receive $23.4M for Pathogen Genome Database

The NIH award funds a database that catalogs genomic information of clinically, economically, and scientifically important eukaryotic pathogens.

Nov 12, 2014

Study Teases Out Truly Drug-sensitive ALK Mutations ahead of Neuroblastoma Phase III Trial

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NEW YORK (Genomeweb) — A study comprehensively analyzing the genomes of more than 1,500 neuroblastoma cases has better determined the prognostic significance of ALK mutations and other alterations in neuroblastoma, and has biochemically investigated many of these variants to determine which ones

Oct 15, 2014

UPenn Awards $6.9M in Research Grants to Advance Treatment of BRCA-related Cancers

NEW YORK (GenomeWeb) – The University of Pennsylvania's Basser Research Center for BRCA said it will award $6.9 million in research grants to its own investigators and those at other US institutions working on projects to advance cancer treatments for patients harboring BRCA1 and BRCA2 mutations

Oct 03, 2014

Study Suggests Biased Gene Conversion Can Ratchet up Homozygosity, Recessive Disease Risk

NEW YORK (GenomeWeb) – Recessive inherited disease risk may be incrementally notched up over time in human populations by a process called biased gene conversion, according to a study appearing online yesterday

Sep 16, 2014

Wistar, Penn Win $12.1M in NCI Funds for Melanoma Studies

NEW YORK (GenomeWeb) – The Wistar Institute has received a $12.1 million grant from the National Cancer Institute to fund collaborative research projects with University of Pennsylvania scientists focused on developing targeted skin cancer therapies, Wistar said on Tuesday.

Aug 04, 2014

Penn's Perelman School Reels in $7.3M for Esophageal Cancer Research

NEW YORK (GenomeWeb) – The Perelman School of Medicine at the University of Pennsylvania has received a $7.3 million grant from the National Cancer Institute for three research projects targeting genes and proteins involved in of esophageal cancer.

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The Scan

Keep Them or Not?

NPR says the explosion and fire earlier this week at a Russian lab that stores dangerous pathogens revives the question of whether such samples should be kept.

Dunno Whose It Is

According to Wired, Nebula Genomics is providing a way for people to get their genomes sequenced anonymously.

Knowing Risk From a Young Age

A 26-year-old woman tells Cosmopolitan about learning her APOE status at a young age.

Science Translational Medicine Paper Finds Drug Combo Boosts KRAS Inhibitor Efficacy in Lung Cancer

In Science journals this week: a functional genomic screen uncovers drug combination that increases KRAS inhibitor efficacy in aggressive lung cancer, and more.

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