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Jun 22, 2016

NIH Panel Approves CRISPR-Edited T Cell Safety Trial, First In-Human Use

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The UPenn-led study proposal calls for editing three genes in autologous T cells with CRISPR and includes preliminary data for on- and off-target editing.

Jun 17, 2016

CRISPR Proposal to Be Reviewed

A safety panel is to review a proposal next week to use CRISPR as part of a cancer treatment, Technology Review reports.

Jun 17, 2016

Q&A: Penn's Garret Fitzgerald Discusses Pertinence and Politics of NAM Biomarkers Report

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A member of the committee issuing a blunt report on the inadequacy of biomarker-based testing speaks about what the next Secretary of HHS needs to do.

Jun 08, 2016

University of Pennsylvania Cofounds BluePen Biomarkers to Create Biomarker Discovery Pipeline

The university formed the new venture in collaboration with Blueprint Bio and Emerald Logic in order to discover biomarkers for personalized medicine.

May 05, 2016

Families at Risk for Breast Cancer Gain Little Benefit, More Uncertainty From Expanded Gene Panel

Researchers saw an 'incremental clinical benefit' from analyzing 180 genes in the exomes of hundreds of individuals from families affected by breast or ovarian cancer.

Apr 18, 2016

UPenn Center for Personalized Dx Expands Tumor NGS Menu, Reports Concordance With Single-Gene Tests

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The group compared results of 304 cancer specimens tested by both NGS and one or more single-gene tests, showing almost complete concordance.

Apr 13, 2016

Parker Foundation Launches $250M Collaborative Institute for Cancer Immunotherapy

The institute will combine expertise from six cancer centers in the US in order to drive research and drug development in cancer immunotherapy. 

Mar 29, 2016

Metagenomic Sequencing Study IDs Viral Particles Transferred During Fecal Transplantation

Researchers identified bacteria-infecting viruses transmitted from a healthy donor to children with ulcerative colitis during fecal transplantation.

Mar 22, 2016

Researchers Sequence Chimpanzee Parasites to Learn About Evolution of Human Malaria Species

The research team used selective amplification to sequence whole genomes of the parasites, revealing new information about how they evolved to infect human hosts. 

Jan 07, 2016

Study Finds Genetic Overlap Between Dilated Cardiomyopathy and Pregnancy-Related Heart Failure

A significant proportion of women with peripartum cardiomyopathy had truncating mutations in genes previously implicated in dilated cardiomyopathy.

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The Scan

So, So Many

According to Gizmodo, researchers have developed a list of a million nucleic acid-like polymers that could store genetic information.

Golden Rice Soon?

An opinion piece in the Washington Post argues that golden rice could save the sight and lives of many children.

To Share More

US National Institutes of Health has issued a new draft data-sharing policy, ScienceInsider reports.

Cell Studies Assess Hepatocellular Carcinoma Immune Cells, Renal Cell Carcinoma, More

In Cell this week: analysis of immune microenvironment in hepatocellular carcinoma, proteogenomic analysis of clear cell renal cell carcinoma, and more.

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