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Oct 03, 2016

Germline Mutations Uncovered Through Tumor Sequencing Present Challenges for Providers

Clinicians and genetic counselors are coming up with triage strategies for cancer cases in which medically actionable germline mutations are suspected.

Sep 20, 2016

UPenn Engineers Develop Instrument-Free Zika MDx, Immunoassay

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The device, which will be tested in collaboration with a Panamanian research institute, will run 40-minute tests without the need for electricity.

Jun 24, 2016

UPenn-Led Consortium Awarded $10.8M NIH Grant to Study Genomics of Alzheimer's Disease

UPenn will establish the Coordinating Center for Genetics and Genomics of Alzheimer's Disease in collaboration with five other institutions.

Jun 22, 2016

NIH Panel Approves CRISPR-Edited T Cell Safety Trial, First In-Human Use

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The UPenn-led study proposal calls for editing three genes in autologous T cells with CRISPR and includes preliminary data for on- and off-target editing.

Jun 17, 2016

CRISPR Proposal to Be Reviewed

A safety panel is to review a proposal next week to use CRISPR as part of a cancer treatment, Technology Review reports.

Jun 17, 2016

Q&A: Penn's Garret Fitzgerald Discusses Pertinence and Politics of NAM Biomarkers Report

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A member of the committee issuing a blunt report on the inadequacy of biomarker-based testing speaks about what the next Secretary of HHS needs to do.

Jun 08, 2016

University of Pennsylvania Cofounds BluePen Biomarkers to Create Biomarker Discovery Pipeline

The university formed the new venture in collaboration with Blueprint Bio and Emerald Logic in order to discover biomarkers for personalized medicine.

May 05, 2016

Families at Risk for Breast Cancer Gain Little Benefit, More Uncertainty From Expanded Gene Panel

Researchers saw an 'incremental clinical benefit' from analyzing 180 genes in the exomes of hundreds of individuals from families affected by breast or ovarian cancer.

Apr 18, 2016

UPenn Center for Personalized Dx Expands Tumor NGS Menu, Reports Concordance With Single-Gene Tests

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The group compared results of 304 cancer specimens tested by both NGS and one or more single-gene tests, showing almost complete concordance.

Apr 13, 2016

Parker Foundation Launches $250M Collaborative Institute for Cancer Immunotherapy

The institute will combine expertise from six cancer centers in the US in order to drive research and drug development in cancer immunotherapy. 

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The Scan

Hundreds and Hundreds Retracted

The Washington Post reports that a Russian Academy of Sciences commission has led to the retraction of hundreds of scientific papers.

Guilty Plea in Kickback Case

The Los Angeles Times' Daily Pilot reports the chief executive of Vantari Genetics has pleaded guilty in a kickback scheme.

Florida Bill Moves Ahead

News 4 Jax reports that a Florida bill to prevent life and long-term care insurers from using genetic information in their coverage decisions has easily passed one committee.

Science Presents Studies Into Disease-Causing Mutations Among Bone Marrow Donors; Links Between Heavy Drinking, Other Disease

In Science this week: potentially pathogenic mutations found in hematopoietic stem cells from young healthy donors, and more.

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