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The UPenn-led study proposal calls for editing three genes in autologous T cells with CRISPR and includes preliminary data for on- and off-target editing.

A safety panel is to review a proposal next week to use CRISPR as part of a cancer treatment, Technology Review reports.

A member of the committee issuing a blunt report on the inadequacy of biomarker-based testing speaks about what the next Secretary of HHS needs to do.

The university formed the new venture in collaboration with Blueprint Bio and Emerald Logic in order to discover biomarkers for personalized medicine.

Researchers saw an 'incremental clinical benefit' from analyzing 180 genes in the exomes of hundreds of individuals from families affected by breast or ovarian cancer.

The group compared results of 304 cancer specimens tested by both NGS and one or more single-gene tests, showing almost complete concordance.

The institute will combine expertise from six cancer centers in the US in order to drive research and drug development in cancer immunotherapy. 

Researchers identified bacteria-infecting viruses transmitted from a healthy donor to children with ulcerative colitis during fecal transplantation.

The research team used selective amplification to sequence whole genomes of the parasites, revealing new information about how they evolved to infect human hosts. 

A significant proportion of women with peripartum cardiomyopathy had truncating mutations in genes previously implicated in dilated cardiomyopathy.

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The US Patent and Trademark Office is opening another interference proceeding in the CRISPR patent fight.

There's increasing genetic evidence that a number of ancient hominins may have contributed to the human gene pool, according to Discover's The Crux blog.

The Japan News writes that Japan needs to seize the opportunity to ensure that a wide number of people benefit from personalized cancer treatments.

In Cell this week: messenger RNA expression and translation, RNA localization atlas, and more.