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In Nucleic Acids Research this week: Planteome database of reference plant ontologies and other data; algorithm to find rearrangements in cancer genomes; and more.

Penn bioinformaticians are testing REALGAR, an application to simplify searches of GWAS, WGS, RNA-seq, and other test results for wet-lab researchers.

University of Pennsylvania researchers sequenced single mitochondria, which they noted could be used to track the development of mitochondrial disease.

Investigators have established hundreds of patient-derived xenografts, cell lines, and tumor samples, which appear to represent a wide range of melanoma molecular subtypes.

In the African American arm of a new GWAS, a risk variant in the SEMA3A gene was associated with both alcohol dependence disorder and major depressive disorder.

A genome-wide association study involving almost 1,600 African individuals led to diverse skin pigmentation-associated loci with varied effects on the complex trait.

A new set of papers reveals a range of gene expression influencers, identified using thousands of samples collected for the Genotype-Tissue Expression project.

Beyond BRCA

Mutations in other genes like PALB2 also confer breast cancer risk, the Philadelphia Inquirer writes.

Using data for 34 individuals, researchers tallied human DNA methylation variation across Yakut, Cambodian, Pathan, Mozabite, and Mayan populations.

Investigators identified ties between autism spectrum disorder and mitochondrial haplogroups in mtDNA variant data from nearly 1,000 ASD-affected families.

Pages

The Hill reports President Donald Trump issued an executive directing federal agencies to cut the number of board and advisory committees they have.

The New York Times reports that researchers are combining tools to more quickly develop crops to feed a growing population and cope with shifting climates.

Scientists in Canada are looking to the UK's plan to sequence children with rare conditions for inspiration, the National Post reports.

In PNAS this week: copy number changes arose during polar bear evolution, genomic and transcriptomic analysis of the Siberian hamster, and more.