Close Menu


Mayo Clinic, University of Pennsylvania, GE Healthcare, EraGen Biosciences, Focus Diagnostics, Roche Nimblegen, and Stratatech are awarded US patents.

By comparing mice exposed to different diet regimens, University of Pennsylvania researchers have garnered evidence suggesting calorie restriction and fat withdrawal lead to changes in the expression and methylation of certain stress-related genes in parts of the mouse brain.

Paired Ends: Nov 30, 2010


Vivian Cheung

By genotyping more than 1,000 individuals with anorexia nervosa and almost 4,000 unaffected controls, researchers have identified common SNPs and rare CNVs that appear to be linked to the condition.

The results of one study indicate that "there is room to improve the clarity of the information provided to customers in their personal genetic test result reports and the way the information is being delivered to them."

Over the next three years, PGFI said today, it will spend $2 million on next-generation sequencing equipment, and $3 million on projects focusing on applications of next-gen sequencing to health and disease.

At the ASHG annual meeting Friday, a group of experts discussed everything from consumer attitudes about direct-to-consumer genetic testing to oversight of such tests.

An American research team is using matched RNA and DNA sequence data to find RNA-DNA differences in the human genome that may be examples of post-transcriptional RNA editing.

Although the study published in NEJM showed that 81 percent of melanoma patients responded to PLX4032, some questions remain about how and why patients are developing resistance to the therapy, and whether the drug improves overall survival.

The publication closely follows a paper by a Dutch group that also showed DNA traversing a nanopore. The Penn team used a method called chemical vapor deposition to grow the graphene on a copper substrate, while the Dutch team used an exfoliation approach to construct its nanopore.


The Wall Street Journal reports that Russia's announcement of a coronavirus vaccine approval was met with concern as safety testing has not yet been completed.

New Scientist writes there aren't much data available on the accuracy of the two rapid COVID-19 tests the UK plans to roll out.

In PNAS this week: downstream effect of oncoprotein fusion, epigenetic changes influence tRNAs in colon cancer, and more.

Nature News reports that recent proposed changes to the US National Science Foundation have raised concerns about a shift away from the agency's focus on basic research.