By comparing mice exposed to different diet regimens, University of Pennsylvania researchers have garnered evidence suggesting calorie restriction and fat withdrawal lead to changes in the expression and methylation of certain stress-related genes in parts of the mouse brain.
The results of one study indicate that "there is room to improve the clarity of the information provided to customers in their personal genetic test result reports and the way the information is being delivered to them."
Over the next three years, PGFI said today, it will spend $2 million on next-generation sequencing equipment, and $3 million on projects focusing on applications of next-gen sequencing to health and disease.
Although the study published in NEJM showed that 81 percent of melanoma patients responded to PLX4032, some questions remain about how and why patients are developing resistance to the therapy, and whether the drug improves overall survival.
The publication closely follows a paper by a Dutch group that also showed DNA traversing a nanopore. The Penn team used a method called chemical vapor deposition to grow the graphene on a copper substrate, while the Dutch team used an exfoliation approach to construct its nanopore.