UPenn

Isoma, which launched last year, will use the funds to develop and clinically validate a molecular test for stratifying glioblastoma patients.

CRISPR Regulation

In an essay at Foreign Affairs, University of Pennsylvania researchers discuss how to best regulate CRISPR gene editing.

This Week in PNAS

In PNAS this week: population structure in Helicoverpa, AMP-activated protein kinase levels in nicotine-exposed mice, and more.

Chromatin immunoprecipitation sequencing showed divergent H4K16ac histone acetylation patterns in brain samples from young, old, and AD-affected individuals.

Researchers are exploring alternative ways to return genetic testing results to grapple with the anticipated increase in testing and see a role for the web.

Using exome sequence and questionnaire data, researchers saw links between motor skills and likely gene disruptive or missense de novo mutations.

Technology Review reports that animals given large gene therapies doses have suffered fatal side effects.

Expanded Indications

The FDA has expanded the indications for both AstraZeneca's PARP inhibitor Lynparza and Myriad Genetics' BRACAnalysis CDx test, as GenomeWeb reports.

In Nucleic Acids Research this week: Planteome database of reference plant ontologies and other data; algorithm to find rearrangements in cancer genomes; and more.

Penn bioinformaticians are testing REALGAR, an application to simplify searches of GWAS, WGS, RNA-seq, and other test results for wet-lab researchers.

Pages

A draft bill released by the US House of Representatives appropriations committee would increase the 2019 National Institutes of Health budget by 3 percent.

Bloomberg looks into privacy issues raised by law enforcement's use of genetic genealogy sites.

NBC News reports on the Earth BioGenome Project, which aims to sequence all eukaryotic life on Earth.

In Science this week: environmental DNA can help in studies of marine animals, and more.