UPenn BostonGene, Abramson Cancer Center to Collaborate on Immunotherapy Studies The agreement will support multiple research projects at UPenn, beginning with a study of tumor-specific antigens for personalized cancer vaccine development. Combination of Sequencing, EHR Data Links Genes to Range of Conditions The exome-by-phenome-wide analysis uncovered 21 novel gene-phenotype associations, including genes linked to glaucoma and diabetes. Alzheimer's Disease Linked to Epigenetic Changes in Multi-Omic Study Investigators identified disease-associated histone modifications in the brain that appeared to influence transcription- and chromatin-related processes. New Methods Boost Scale of Single-Cell Gene Expression Dynamics Studies Premium Labs are finding cheaper, higher-throughput ways to determine the inflection points in gene expression within a particular cell. Heritable Gene Expression in Single Cells Leads to Subpopulations With Marked Behaviors Researchers have developed a method, called MemorySeq, to identify genes transcriptome-wide whose expression fluctuations persist for several cell divisions. Jul 14, 2020 Genetic Alterations in Cyclin-Dependent Kinases Highlight Potential Cancer Treatment Approach Jun 16, 2020 Multi-Ancestry Type 2 Diabetes Genetic Study Discovers Hundreds of Novel Loci Jun 2, 2020 Evidence for Targeted Treatment Builds in Cancers of Unknown Primary but Randomized Data Pending Premium May 31, 2020 Oncologists Make Progress Toward Showing Utility for Brain Cancer Liquid Biopsy Apr 16, 2020 Multi-Analyte Liquid Biopsy Panel May Aid in Pancreatic Cancer Detection, Staging Premium Apr 15, 2020 Infant Gut Virome Influenced by Breastfeeding, Metagenomic Analysis Finds Mar 19, 2020 Imaging Could Help ID Brain Cancer Patients Eligible for Plasma Testing Premium Mar 6, 2020 CHOP Shares Insights, Experience From Centralized Genomic Medicine Lab Premium Feb 25, 2020 Epic EMR Users Begin Integrating Genomics Data for Clinical Decision Support Premium Nov 20, 2019 Host Expression Provides Treatment Response Clues in Cutaneous Leishmaniasis Oct 30, 2019 Liquid Biopsy Shows Promise in New Brain Cancer Study Oct 8, 2019 Genetics Contributed to Variations in Height Among Ancient Europeans Aug 15, 2019 Germline Genome Editing Governance Weighed by International Commission Premium Jul 2, 2019 Dilated Cardiomyopathy Risk Increased in Only Some With Titin Truncations May 31, 2019 Single-Cell Sequencing Proves Useful for Tracking Drug-Resistant AML Mutation Progression Premium May 1, 2019 Cleft Palate Study Shows Transcription Factor, Enhancer Roles in Related Developmental Processes May 1, 2019 Genetic Variation Influences People's Perception of Odors Apr 2, 2019 Treatment With Less Toxic Rubraca in Molecularly-Defined Pancreatic Cancer Subset Proposed at AACR Premium Mar 22, 2019 Spontaneous Preterm Birth Clues Identified in Cervicovaginal Microbiome Feb 19, 2019 East African Hunter-Gatherer Populations Share Common Genetic Ancestry Load More Breaking News Ancient DNA Analysis Highlights Three Ancestral Populations in Japan FDA Warns of Potential False Positives With Abbott SARS-CoV-2 Molecular Tests New Products Posted to GenomeWeb: Oxford Nanopore, Beckman Coulter, Thermo Fisher Scientific, More People in the News: New Appointments at Sema4, NHGRI, Dante Labs, Ancestry, More Thermo Fisher Scientific Expects 12 Percent Revenue Growth in 2022 In Brief This Week: Myriad Genetics, Danaher, Co-Diagnostics, and More The Scan For Those Thick Tiger Stripes Tigers in India with thick stripes harbor a genetic change, as Gizmodo reports. High GABA Tomatoes The Japan News reports that genome-edited tomatoes with higher GABA levels are now for sale in Japan. Approach for Inclusivity and Diversity A National Human Genome Research Institute team calls for the field to "adopt diversity as an ethos." Science Papers on Tumors Immune System Evasion; Drivers of Genomic Instability, Inflammation In Science this week: study of how tumors evade the adaptive immune system, and more.