UPenn
Heart Failure Genetic Study Highlights Interplay Between Common, Rare Risk Variants
Along with rare disease variants found in exome or genome sequence data, researchers identified common variants that combine to influence heart failure risk.
The CAD iPRS seeks to provide more holistic personalized risk assessments by combining clinical risk factors with genomic ones.
Brain Cancer Study Reveals Immune Cell Populations Linked to Aggressive Subtype
Researchers used single-cell RNA sequencing and spatial transcriptomics to find two myeloid-derived suppressor cell subsets supporting the growth of an aggressive glioblastoma.
The Solvd Health AvertD assay for opioid use disorder risk could lead to false negative and false positive results, according to a study led by University of Pennsylvania researchers.
Individuals were assigned both the highest and lowest risk for coronary heart disease depending on the polygenic risk score used to evaluate them.