The group aims to collect and sequence more than 2,500 blood samples by 2020 to improve primary diagnosis and treatment options for patients suffering from Parkinson's disease.
With RNA sequence, expression quantitative trait locus, genome-wide association, and other data, researchers identified disease-related genes in the kidney glomerulus and tubule compartments.
The researchers characterized how gene therapy affects the immune cell repertoires and microbiomes of X-linked severe combined immunodeficiency patients.
Plasmodium vivax parasites that infect humans have highly similar genomes to parasites that infect apes, a finding with possible disease-eradication consequences.
Three immunology researchers are to receive this year's Albany Medical Center Prize in Medicine and Biomedical Research, the Albany Times-Union reports.
The UPenn team will collect genetic information from outside patient cohorts, reorganize it in a streamlined process, and provide a database for downstream studies.
In Genome Biology this week: processing and analyzing single-cell transcriptome data, computational strategy for designing CRISRP single guide RNAs, and more.
In an editorial, officials from scientific societies in the US and China call for the international community to develop criteria and standards for human germline editing.
The US National Institutes of Health is to review studies that have received private support for conflicts of interest, according to the New York Times.
