The new method, called sci-Plex, combines nuclear hashing and improved single-cell combinatorial indexing RNA-seq to profile the transcriptional response of single cells.
In PNAS this week: cytotoxic CD4 T cell signature in supercentenarians, evolutionary history of beetles, and more.
With a $3.7 million NIH grant, database developers hope to garner FDA recognition, develop a new user interface, and further integrate its use in cancer care.
In PNAS this week: analysis of extensively drug-resistant Mycobacterium tuberculosis strain, regulation of obesity-linked gene, and more.
Researchers uncovered examples of potentially beneficial copy number variants introgressed from Neanderthals and Denisovans under positive selection in Melanesians.
Researchers explore a possible genetic cause for some cases of sudden infant death syndrome, KOMO News reports.
The Seattle startup is looking to partner with pharmaceutical companies and offer its yeast fusion sequencing technology as a contracted research service.
The team saw risky mutations in colorectal cancer, polyp, and Lynch syndrome-related genes in almost 4 percent of CRC patients diagnosed at 72 years old, on average.
Discover's The Crux blog writes that the expression of some genes ramp up after an organism dies.
The software, presented at the ISMB/ECCB conference, helps researchers fill in gaps in the human epigenome thanks to 3D deep-learning techniques.
A genetic alteration appears to increase heart failure risk among people of African descent, according to the Washington Post.
Gene editing could be an issue competitive sports need to address soon, four researchers from Arizona State University write at Slate.
In his look back at the past decade, BuzzFeed News' Peter Aldhous writes that direct-to-consumer genetic testing has led to "Facebook for genes."
In Nature this week: genetic "clock" that can predict the lifespans of vertebrates, new assembler called wtdbg2, and more.