The team saw risky mutations in colorectal cancer, polyp, and Lynch syndrome-related genes in almost 4 percent of CRC patients diagnosed at 72 years old, on average.
The researchers found that background TP53 gene mutations increase with age and could affect efforts to develop liquid biopsy-based cancer screening tests.
The virology department at UW will offer a number of support services to diagnostics developers, including particular expertise in digital PCR and sequencing technologies.
Common non-coding variants, along with rarer coding alterations, appear to contribute to a developmental disease with bowel and other gastrointestinal symptoms.
In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.
