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University of Virginia

Single-Nucleus Chromatin Accessibility Profiling in Coronary Artery Disease Points to Mechanisms

The researchers analyzed more than 28,000 cells using single-nucleus ATAC-seq to develop an atlas of genome accessibility.

Polygenic Transcriptome Risk Scores for COPD Show Improved Cross-Ancestry Portability

Researchers found that polygenic transcriptome risk scores worked better across ethnicities than polygenic risk scores to predict chronic obstructive pulmonary disease risk.

Ceres Nanosciences Hydrogel Technology Shows Promise for Capturing Circulating Tumor DNA
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Ceres plans to develop its Nanotrap technology to isolate undetectable levels of circulating tumor DNA in blood samples from non-small cell lung cancer patients.

New $22M Study to Use Sequencing, Proteomics to Investigate Pulmonary Fibrosis

Among the study's goals is to identify molecular signatures that can distinguish idiopathic pulmonary fibrosis from interstitial lung disease.

UVA Teams Wins $2.7M NIH Grant to Study Genetic Variation in Atherosclerosis

The scientists aim to use single-cell analysis to investigate the role of variation in a gene called ID3 in vascular smooth muscle cells.

Apr 23, 2019

Cell Microsystems Awarded $1.6M NIH Grant for Single Cell Analysis

Jan 25, 2019

Biomedicine, Genomics Priorities at New UVA School of Data Science
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Nov 12, 2018

DNA Methylation Changes Uncovered in Undernourished Children

Mar 22, 2018

UVA-Led Group Using NCI Grant to ID Common Genetic Mechanisms Affecting Cancer Risk
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Dec 1, 2017

Kidney Transplant Tolerance Signatures Provide Clues to Curbing Excess Immunosuppression

Aug 17, 2017

Amebic Infection Severity May Decline as Gut Microbial Diversity Increases

Oct 5, 2016

Quantitative PCR Gives New Insights on Large Study of Childhood Diarrhea in Africa, Asia
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May 28, 2014

Report: Regulatory Authority Exists to Oversee Synthetic Biology, but Challenges Remain

Oct 17, 2013

US Subsidiary of ZyGem Shuttered After Forced Bankruptcy; Questions Surround Asset Disbursement
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Feb 9, 2012

UVA Researchers with ZyGem Ties Develop Multiplexed Chip-Based Warfarin Genotyping Assay
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Jan 13, 2012

U of Virginia Team IDs Possible Biomarkers for Detecting Early Atherosclerosis

Oct 11, 2011

NCI Awards $9.6M for Research into Therapy-Resistant Prostate Cancer

Oct 7, 2011

Sequencing Study Finds Few Rearrangements in Mouse Induced Pluripotent Stem Cells

Nov 30, 2010

UVA-Led Research Team Partners with OGT on 10,000-Sample Type 1 Diabetes Study
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Oct 28, 2010

IP Watch: Recent Patents Related to PCR, Nucleic Acid Amplification, and Sample Prep: Oct 28, 2010
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Jul 30, 2010

Funding Update for Jul 30, 2010
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Jul 16, 2010

Recent Patents of Interest in Proteomics: Jul 16, 2010
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Oct 30, 2009

Q&A: With New Innovator Award, UVA's Hall Will Develop Tools to Study Genomic Structural Variation
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Oct 6, 2009

NHLBI Grants $64.5M in Stimulus Funds for Exome Sequencing of Well-Phenotyped Cohorts
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Sep 21, 2009

Duke Genome Center Lands $20M DARPA Grant

Breaking News
The Scan

Nucleotide Base Detected on Near-Earth Asteroid

Among other intriguing compounds, researchers find the nucleotide uracil, a component of RNA sequences, in samples collected from the near-Earth asteroid Ryugu, as they report in Nature Communications.

Clinical Trial Participants, Investigators Point to Importance of Clinical Trial Results Reporting in Canadian Study

Public reporting on clinical trial results is crucial, according to qualitative interviews with clinical trial participants, investigators, and organizers from three provinces appearing in BMJ Open.

Old Order Amish Analysis Highlights Autozygosity, Potential Ties to Blood Measures

Researchers in BMC Genomics see larger and more frequent runs-of-homozygosity in Old Order Amish participants, though only regional autozygosity coincided with two blood-based measures.

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.