University of Utah

This Week in PNAS

In PNAS this week: influence of DNA architecture on genome editing, within-host HIV evolution, and more.

A new study shows that DNA targets bound by nucleosomes are cleaved less efficiently than targets lacking nucleosomes, which could inform target selection.

Researchers used WGS to diagnose the patients when previous testing couldn't find an underlying genetic cause for their symptoms.

This Week in PNAS

In PNAS this week: Smyd1 regulates mitochondrial metabolism in the heart, evolutionary history of ASICs, and more.

This Week in Cell

In Cell this week: sequencing to understand medulloblastoma metastases, genome and transcriptome implicates TAP1 in X-linked Dystonia-Parkinsonism, and more.

Researchers discovered thousands of candidate functional elements by searching diverse mammalian genomes for regions of accelerated evolution within highly conserved sites.

Researchers found rare mutations in USP45 and ARID1A by applying a shared genomic segment mapping approach to several large multiple myeloma-affected families.

Some Guarded Hope

The Deseret News reports that families with children with rare genetic diseases are cautiously optimistic about CRISPR-based gene editing as a treatment.

This Week in Nature

In Nature this week: a genomics search engine, and more.

Living DNA and its partners are aiming to create a detailed genetic map of the world based on people's DNA.

Pages

The UK's Human Fertility and Embryology Authority calls for consumer genetic testing companies to warn customers that testing could uncover family secrets, according to the Guardian.

The New York Times reports that United Nations delegates have been discussing how to govern the genetic resources of the deep sea.

Researchers have transplanted edited cells into mice that appear to combat cocaine addiction, New Scientist reports.

In PNAS this week: analysis of proteolytic enzymes secreted by circulating tumor cells, phylogenetic study of Fv1 evolution, and more.