A new study shows that DNA targets bound by nucleosomes are cleaved less efficiently than targets lacking nucleosomes, which could inform target selection.
In Cell this week: sequencing to understand medulloblastoma metastases, genome and transcriptome implicates TAP1 in X-linked Dystonia-Parkinsonism, and more.
Researchers discovered thousands of candidate functional elements by searching diverse mammalian genomes for regions of accelerated evolution within highly conserved sites.
Researchers found rare mutations in USP45 and ARID1A by applying a shared genomic segment mapping approach to several large multiple myeloma-affected families.
The Deseret News reports that families with children with rare genetic diseases are cautiously optimistic about CRISPR-based gene editing as a treatment.
The UK's Human Fertility and Embryology Authority calls for consumer genetic testing companies to warn customers that testing could uncover family secrets, according to the Guardian.
