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University of Toronto

Autophagy-associated genes appear to be important for immune evasion, but losing multiple of these genes could also make cancers resistant to T cell activity.

In Cell this week: proteomic and metabolomic analysis of blood from COVID-19 patients, change in phosphorylation with infection, and more.

Investigators reported that methylation profiling could distinguish brain cancer subtypes and could detect kidney cancer with striking sensitivity in early experiments.

Blood-Sucking Genome

The draft European medicinal leech genome reveals more than a dozen putative anticoagulants.

In PLOS this week: genome-wide association study of agronomic traits in sugarcane, breastfeeding can modulate body-mass index among individuals at genetic risk of obesity, and more.

New analyses indicate female researchers are publishing less during the coronavirus pandemic than male researchers, according to Nature News.

The study suggests that pediatric low-grade gliomas driven by genetic rearrangements tend to be diagnosed earlier and have better outcomes than those driven by SNVs.

The protein-protein interactions tallied in the project are expected to inform future studies of biology and disease in various tissue and cell types.

In Nature this week:  three-dimensional assay to visualize transposase-accessible chromatin, computational tool that uses variant information to map cells to clone of origin, and more.

The screen, which multiplexes Cas9 and Cas12a, could be used for functional analysis of large genomic regions in mammalian cells, the researchers said.

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Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.