University of Toronto

The single approach could be useful in some of the same areas where combinations of technologies have been implemented, such as AR-V7 testing in prostate cancer.

This Week in PLOS

In PLOS this week: genetic drift influences diversity among pathogens, QTLs linked to benzimidazole sensitivity, and more.

This Week in Cell

In Cell this week: sequencing to understand medulloblastoma metastases, genome and transcriptome implicates TAP1 in X-linked Dystonia-Parkinsonism, and more.

This Week in PNAS

In PNAS this week: method to predict cancer susceptibility, root microbiome, and more.

Expression and copy number profiles from histologically normal duct tissue near tumors suggest a "field of cancerization" may exist in epithelial cells around cancer.

In Nucleic Acids Research this week: disease network resource, database of epigenetic consequences of de novo mutations, and more.

Using genomic data from large cancer cell line collections, investigators identified versions of spliced genes that spell better or worse drug response.

Such an atlas could enable investigators to understand how genetic variants impact disease risk, define drug toxicities, improve therapies, and advance regenerative medicine.

This Week in PNAS

In PNAS this week: influence of gene environment interactions on polygenic traits, epigenetic features affecting fruit fly foraging, and more.

With exome sequences, RNA sequences, and methylation profiles, investigators uncovered differences between radiation-induced and sporadic forms of meningioma.

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With H3Africa, Charles Rotimi has been working to bolster the representation of African participants and African researchers in genomics, Newsweek reports.

NPR reports that government and private insurers are being slow to cover recently approved CAR-T cell therapies.

CNBC reports that there are thousands of genetic tests available for consumers to chose between.

In Nature this week: genomic analysis of ducks, whole-genome doubling among tumor samples, and more.