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Genome Biology Papers on Tibetan SVs, Lung Cancer Epigenomes, Cancer Regulatory Elements

In Genome Biology this week: structural variants linked to high-altitude adaptations, epigenetic subtypes of lung adenocarcinoma, and more.

Researchers Aim to Improve Lynch Syndrome Testing With Genetic-Epigenetic Combination Method
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The sequencing test involves a single library preparation that is then split for parallel analysis of promoter methylation, MSI calculation, and gene mutation detection.

CNV Analyses May Uncover Mendelian Conditions in Undiagnosed Pediatric Patients

Investigators diagnosed additional Mendelian conditions with copy number variant analyses on pediatric patients who remained undiagnosed after exome sequencing.

Researchers Turn Methylated DNA Profiling Method Towards Prenatal Testing Applications
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At the ASHG 2020 virtual meeting, researchers presented data showing they could use the method to enrich for placental DNA in maternal plasma samples.

Cellular Analytics Eyes Early Mesothelioma Detection Using Liquid Biopsy Tech
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The firm's assay, dubbed MesoFind, uses an immunomagnetic capture method to identify surface antigens on mesothelioma pleural cells in a patient's blood sample.

Jun 26, 2020

Brain, Kidney Cancer Studies Lay Path for Clinical Application of Epigenetic Liquid Biopsy Method
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Apr 13, 2020

Pediatric Low-Grade Glioma Molecular and Clinical Analysis Defines Subtypes That Predict Outcome

Apr 8, 2020

Tens of Thousands of Protein-Protein Interactions Reported in Human Reference Interactome Map

Mar 18, 2020

CRISPR Screening Approach for Mapping Genetic Interactions Uncovers Masked Phenotypes

Mar 12, 2020

Head and Neck Cancer Driver Mutations Affect NOTCH Pathway, CRISPR Screen Finds

Feb 5, 2020

Large-Scale Pan-Cancer Analysis Expands Set of Alterations Disrupting Key Genes, Pathways

Jan 7, 2020

Circulating Tumor Cell Collection, Analysis Methods Make Headway in 2019
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Dec 12, 2019

Online Tool to Select Secondary Findings May Shorten Genetic Counseling Sessions

Nov 6, 2019

Cellular Analytics Eyes Drug Development Space with Circulating Tumor Cell Capture Platform
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Oct 7, 2019

Prostate Cancer Methylation Levels Linked to Regulatory Variants in Germline

May 3, 2019

Differential Methylation of Enhancer May Lead to Abnormal Dopamine Levels in Major Psychosis

Feb 7, 2019

Cancer-Associated Circular RNAs Catalogued Across Tumor Types

Feb 4, 2019

Genome Canada, Partners Award $42.6M in Genomics, Informatics Research Funding

Jan 14, 2019

Risky Behavior Tied to Hundreds of Loci Through Large GWAS Analysis

Jan 2, 2019

Circulating Tumor Cell Capture Technologies Expand in 2018
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Nov 21, 2018

Immunoprecipitation Method Could Improve Epigenetic Early Cancer Detection Tests
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Nov 14, 2018

Methylation-Based Cancer Early Detection Method Shows Promise in Preliminary Studies

Sep 17, 2018

NGS-Based Post-Transplant Acute Myeloid Leukemia Assay Predicts Relapse Risk
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Aug 30, 2018

Subset of Ewing Sarcomas Arise from Early, Complex Genome Rearrangements

Apr 6, 2018

Researchers Debut Method for Combined Separation, Gene Expression Analysis of CTCs
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Breaking News
The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge is weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.