In a recent study in Blood, the researchers showed that a higher allelic burden after transplantation was associated with higher risk of relapse and mortality.
In Genome Biology this week: genome sequencing study of a wild cherry tree, transcriptomic analysis of a planarian model organism, and more.
The results suggest that some Ewing sarcomas could be detected earlier, when they are easier to treat.
The single approach could be useful in some of the same areas where combinations of technologies have been implemented, such as AR-V7 testing in prostate cancer.
In PLOS this week: genetic drift influences diversity among pathogens, QTLs linked to benzimidazole sensitivity, and more.
In Cell this week: sequencing to understand medulloblastoma metastases, genome and transcriptome implicates TAP1 in X-linked Dystonia-Parkinsonism, and more.
In PNAS this week: method to predict cancer susceptibility, root microbiome, and more.
Expression and copy number profiles from histologically normal duct tissue near tumors suggest a "field of cancerization" may exist in epithelial cells around cancer.
In Nucleic Acids Research this week: disease network resource, database of epigenetic consequences of de novo mutations, and more.
Using genomic data from large cancer cell line collections, investigators identified versions of spliced genes that spell better or worse drug response.
The UK's Human Fertility and Embryology Authority calls for consumer genetic testing companies to warn customers that testing could uncover family secrets, according to the Guardian.
The New York Times reports that United Nations delegates have been discussing how to govern the genetic resources of the deep sea.
Researchers have transplanted edited cells into mice that appear to combat cocaine addiction, New Scientist reports.
In PNAS this week: analysis of proteolytic enzymes secreted by circulating tumor cells, phylogenetic study of Fv1 evolution, and more.