Investigators diagnosed additional Mendelian conditions with copy number variant analyses on pediatric patients who remained undiagnosed after exome sequencing.
The firm's assay, dubbed MesoFind, uses an immunomagnetic capture method to identify surface antigens on mesothelioma pleural cells in a patient's blood sample.
Autophagy-associated genes appear to be important for immune evasion, but losing multiple of these genes could also make cancers resistant to T cell activity.
Investigators reported that methylation profiling could distinguish brain cancer subtypes and could detect kidney cancer with striking sensitivity in early experiments.
In PLOS this week: genome-wide association study of agronomic traits in sugarcane, breastfeeding can modulate body-mass index among individuals at genetic risk of obesity, and more.
The study suggests that pediatric low-grade gliomas driven by genetic rearrangements tend to be diagnosed earlier and have better outcomes than those driven by SNVs.
The New York Times reports that experts say President Joe Biden's goal of vaccinating 1 million people a day in the US in the next 100 days is too low a bar.
