University of Tokyo

Independent research teams took a look at the mutations, gene fusions, and other alterations that may inform pediatric T-ALL treatment and outcome predictions.

Mutation, structural variant, and expression data for up to three dozen TNBCs led to a subset of tumors with homologous recombination changes.

The licenses cover IP related to a new CRISPR technology known as Cpf1, advanced forms of Cas9, and additional Cas9-based genome editing technologies.

Japanese researchers uncovered recurrent DUX4 fusions in adolescent or young adult cases of B-cell acute lymphoblastic leukemia, along with other new ALL fusions.

Filamentous fungi are used in a variety of industrial processes and genome editing could increase enzyme yield and efficiency. 

A trend towards more precise Cas9 activity promises spatial and temporal control over the nuclease and could reduce risky off-target activity in gene editing.

General Electric has been awarded

NEW YORK (GenomeWeb) – Using a phylogenetic-based approach to study the genomes of more than a dozen mammals, University of Tokyo researchers found that African elephants have the largest number of characterized olfactory receptor genes.

NEW YORK (GenomeWeb News) – A single gene appears to be the main culprit in a myeloid proliferation complication called transient abnormal myelopoiesis, or TAM, that's sometimes seen in individuals with Down syndrome, according to a study online yesterday in Nature Genetics, which used

NEW YORK (GenomeWeb News) – A pair of studies appearing in Nature Genetics yesterday reported on a number of variants linked to myeloma, including a variant located near a gene involved in telomere function and ones linked to the cohesin complex.

Pages

Gene drives might run into biological resistance, the Economist reports.

Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.

Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.

In Science this week: full CRISPR locus integration complex structure, and more.