GenomeWeb

University of Texas at Austin

Jul 21, 2020

PNAS Papers on Host Infection Response, RNA Virus Replication, Bidirectional Expression Method

In PNAS this week: role for RTP4 gene in severe malaria, other infections; CRISPR-based approach to alter gene expression; and more.

May 14, 2020

Nature Papers Examine Genetics of Height Among Peruvians, Genetics of Sex-Biased Disease Susceptibility, More

In Nature this week: missense variant linked to decreased height among Peruvians, genetic basis of sex-biased vulnerability to certain disorders, and more.

Jan 31, 2020

Science Studies Examine Genomes of African Population with High Schizophrenia Rate, Engineer Bee Microbiome, More

In Science this week: genetic mutation linked to schizophrenia among South African Xhosas, engineering the bee microbiome to address parasite and virus, and more.

Dec 06, 2019

Science Papers Describe MicroRNA Targeting Efficiency, Approach for Single-Cell High-Throughput Chemical Screens

In Science this week: approach to measure microRNA targeting efficiency, strategy to conduct high-throughput chemical screens at single-cell resolution, and more.

Jun 11, 2019

This Week in PNAS: Jun 11, 2019

In PNAS this week: diversity and spread of Yersinia pestis, local adaptations in switchgrass, and more.

Mar 28, 2019

New Sanger Sequencing Dyes Could Reduce Cost While Maintaining Performance

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An ABRF working group compared three dyes for Sanger sequencing to find that, even with their differences in price, they all performed similarly.

Aug 02, 2018

CRISPR Study Shows Cas12a May Select DNA Target Sequences More Precisely Than Cas9

The researchers showed that Cas12a discriminates strongly against mismatches to DNA targets, leading to less off-target DNA cleavage than with Cas9.

Jun 26, 2018

This Week in PNAS: Jun 26, 2018

In PNAS this week: interactions between tRNA precursor and tumor-suppressing microRNA, sequencing strategy to account for small indels in DNA barcodes, and more.

Apr 26, 2018

ABRF Speakers Outline Disaster Prep for Core Facilities

Speakers at the Association for Biomolecular Resource Facilities annual meeting gave advice on preparing for and recovering from hurricanes.

Mar 27, 2018

Research Teams Reveal Possible Roles of Cas4 in CRISPR Adaptation

One team suggested Cas4 is required to assist the Cas1-2 complex, while the other said Cas4 helps maintain fidelity during CRISPR adaptation.

Breaking News

The Scan

Herbert Tabor Dies

The Washington Post reports that Herbert Tabor, who worked at the US National Institutes of Health for 77 years, has died at 101.

Funds to Get Vaccines

The World Bank is seeking approval for a $12 billion plan to provide low-income nations with funds to procure SARS-CoV-2 vaccines, according to Reuters.

A Number on It

Science writes that public health officials and others are debating whether cycle threshold values should be included on SARS-CoV-2 results.

Nucleic Acids Research Studies on 3D SARS-CoV-2 Structures, Human Brain Atlas, More

In Nucleic Acids Research this week: online database of SARS-CoV-2 protein structures, atlas of the human brain, and more.

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