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In Nature this week: missense variant linked to decreased height among Peruvians, genetic basis of sex-biased vulnerability to certain disorders, and more.
In Science this week: genetic mutation linked to schizophrenia among South African Xhosas, engineering the bee microbiome to address parasite and virus, and more.
In Science this week: approach to measure microRNA targeting efficiency, strategy to conduct high-throughput chemical screens at single-cell resolution, and more.
In PNAS this week: diversity and spread of Yersinia pestis, local adaptations in switchgrass, and more.
An ABRF working group compared three dyes for Sanger sequencing to find that, even with their differences in price, they all performed similarly.
The researchers showed that Cas12a discriminates strongly against mismatches to DNA targets, leading to less off-target DNA cleavage than with Cas9.
In PNAS this week: interactions between tRNA precursor and tumor-suppressing microRNA, sequencing strategy to account for small indels in DNA barcodes, and more.
Speakers at the Association for Biomolecular Resource Facilities annual meeting gave advice on preparing for and recovering from hurricanes.
One team suggested Cas4 is required to assist the Cas1-2 complex, while the other said Cas4 helps maintain fidelity during CRISPR adaptation.
The grants were made as part of the NSF's Enabling Discovery through Genomic Tools — or EDGE — program.
Nature News reports on how meeting cancellations and related costs are affecting scientific societies.
In a new ruling, Canada's Supreme Court upheld the country's genetic non-discrimination law, the Canadian Press reports.
COVID-19 vaccine developers aim to avoid a complication that has affected efforts to develop vaccines for other diseases, the Wall Street Journal reports.
In PLOS this week: analysis of insertions throughout Shigella genomes, antigen production in malaria parasites, and more.