University of Texas at Austin
CRISPR-Associated Nuclease Degrades RNA, DNA to Impair Cell Growth; Promises Use in Biotech
The nuclease, dubbed Cas12a2, is described in two new papers and could potentially be used in a range of biotechnological applications, including as a diagnostic.
Engineered Cas9 Enzyme Less Likely to Make Off-Target Cuts, Still Efficient
After analyzing Cas9 conformations at different points during mismatch cleavage, researchers developed a new enzyme to avoid such cuts.
An ABRF working group compared three dyes for Sanger sequencing to find that, even with their differences in price, they all performed similarly.
CRISPR Study Shows Cas12a May Select DNA Target Sequences More Precisely Than Cas9
The researchers showed that Cas12a discriminates strongly against mismatches to DNA targets, leading to less off-target DNA cleavage than with Cas9.
ABRF Speakers Outline Disaster Prep for Core Facilities
Speakers at the Association for Biomolecular Resource Facilities annual meeting gave advice on preparing for and recovering from hurricanes.