University of Texas
PNAS Papers on Mutation-Phenotype Machine Learning Method, Microviruses, More
In PNAS this week: machine learning tool to assess germline mutation-phenotype links, phage defense mechanisms among microviruses, and more.
Nucleic Acids Research Papers on DeepFun, gutSMASH, COVID-19 Data Portal
In Nucleic Acids Research this week: deep learning approach to gauge consequence of non-coding variants, way to predict primary metabolic gene clusters, and more.
Metastatic Gastric Cancer Outcomes Informed by Single-Cell Transcriptome Profiles
Researchers used single-cell RNA sequencing to delve into intra-tumoral heterogeneity in peritoneal carcinomatosis, identifying a potential prognostic signature.
Nature Papers Describe Future Path for Human Genomic Research, Method to Analyze RNA Structure With Nanopore Sequencing, More
In Nature this week: a framework for future human genomic research, PORE-cupine approach to study RNA structure using nanopore sequencing, and more.
Ebola Virus Appears to Undergo Distinct Changes in Bat, Human Host Cell Line Experiments
Ebola viruses passaged in bat renal cells appeared to be subject to RNA editing by host enzymes, while more adaptive mutations arose after passaging in a human kidney cell line.