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University of Pittsburgh

Diabetes Respite

University of Pittsburgh-led team finds that gene therapy could treat mice with type 1 diabetes for a few months, the Los Angeles Times reports.

In PNAS this week: effect of human genetic variation on CRISPR-Cas9 gene editing, expression profiles of breast cancer, and more.

Oh, the Earlobe

Having free-hanging or attached earlobes might be the work of some 49 different genes, according to a new study.

The funding will support research examining the epigenomic effects of social experiences and how they relate to health disparities.

The seven-gene NGS-based test is available for patients who are found to have pancreatic cysts, and can help physicians decide whether to remove them. 

A research collaboration involving several universities has yielded a technique that they said isolates exosomes from biological samples more effectively than incumbent methods.

In Nature this week: bacteriophage evolution varies based on host, lifestyle, and genetic factors; and more.

Through prospective pancreatic ductal adenocarcinoma testing, researchers saw germline mutations in new genes and in cases outside of current germline testing criteria.

The blood-based test is based on three serum biomarkers —matrix metallopeptidase-9, neuron-specific enolase, and vascular cellular adhesion molecule-1.

The researchers noted that the results "highlight the great potential of nanopore sequencing to analyze broad microbial community trends."

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At the Lancet, more than two dozen public health researchers condemn the conspiracy theories that have emerged surrounding the source of the COVID-19 outbreak.

The Washington Post reports that Philip Leder, who helped uncover how DNA codes for proteins and studied the role of genes in cancer, has died.

Researchers from Trinity College Dublin and the University of Pittsburgh look into how often de novo genes arise and how important they may be.

In Nucleic Acids Research this week: pipeline for genotyping Alu retrotransposon mobile element insertions, previously undocumented non-coding RNAs, and more.