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A co-author of the study said that "the presence or absence of the biomarker can now be used as a diagnostic test to identify which patients will benefit from this drug," and added that their approach can be used to screen the efficacy of any drug for any disease.

Sequenom also said that it amended its license with Isis Innovation for IP underlying its SEQureDx Down syndrome test, which the firm continues to develop following an investigation into mishandled R&D test data and results.

Using genomic, phylogenetic, and biogeographic analyses, British and Danish researchers have found evidence suggesting foamy viruses co-evolved with mammals over millions of years.

Richard Chin, John Rossi, Alice Lin-Tsing, Kenneth Reed

Paired Ends: Apr 28, 2009


Hagan Bayley, Detlef Weigel, Todd Smith, Michael Sadowsky, Catalina Lopez-Correa, Garry Merry

The study is noteworthy because the researchers were able to identify all four bases of DNA in a heteropolymeric background of DNA immobilized inside the pore, according to senior author Hagan Bayley, a professor of chemistry at Oxford.

Bruno Sobral, Michael Gilman, Kathy Gibson, Uwe Christians,Herbert Fritsche, Dan Crowther

The research, published online Sunday in Nature Nanotechnology, is the first to show that scientists can detect unlabeled single DNA bases "to a confidence level … appropriate for a highly competitive commercial sequencing system," Oxford Nanopore's CEO said.

In a paper appearing online in Nature Nanotechnology yesterday, researchers from Oxford Nanopore and the University of Oxford showed that they can accurately distinguish between nucleic acids using protein nanopores coupled to a detection system.


In a cartoon, Vox explores the lack of women among this year's winners of the Nobel Prize.

Science reports a new US defense bill would establish two groups aimed at combating foreign influence on research. 

Nature Biotechnology discusses promising early results from two clinical trials of CRISPR-based therapy for β-thalassemia and sickle cell disease.

In Cell this week: analysis of tissue clones, metagenomic studies of ocean water samples, and more.