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The Oxford team found four distinct classes of mutations in CLL tumors: those that disappeared following treatment; those that remained present at low levels throughout the entire course of treatment; those that expanded; and those that emerged over time.

Researchers are using whole-genome sequencing and targeted deep sequencing to find treatment, remission, and relapse-related mutations in patients with a form of leukemia known as B-cell chronic lymphocytic leukemia.

The new Oxford Cancer Research Centre at Oxford University will receive $4.5 million from Cancer Research UK this year.

By genotyping the major histocompatibility complex gene HLA-DRB1 in individuals from more than 1,000 MS-affected families, researchers have identified sex-specific differences in inheritance patterns for an MS-associated version of the gene.

Two research groups have identified genetic loci linked to polycystic ovary syndrome and endometriosis in individuals of Han Chinese and European descent, respectively.

The advance could eventually give nanopore sequencing an advantage over current methods for identifying methylation sites, such as bisulfite sequencing, because the DNA would not first have to be modified or amplified.

Under the new agreement, which has an undisclosed duration, the company will provide an undisclosed amount of funding to support research in Hagan Bayley's group and will partner exclusively with the university to develop "revolutionary products for molecular analysis" based on discoveries made by the group.

The company will partner exclusively with Oxford University to develop "revolutionary products" for molecular analysis from research done in Bayley's lab, including the development of methods for the direct sequencing of single-stranded DNA.

British and French researchers reported today that they have investigated ties between more than a dozen previously detected, low penetrance risk variants and the risk of developing breast cancer and sub-types of the disease.

After looking for associations between common CNVs and eight common diseases in more than 16,000 affected individuals, members of the Wellcome Trust Case Control Consortium concluded that these CNVs aren't major players in these diseases.

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The Washington Post reports that the CDC's SARS-CoV-2 test issues reflect earlier ones it had with Zika virus testing.

NPR writes that even with thousands of new COVID-19 papers, each should be evaluated based on its own quality.

Researchers traced a gene cluster linked to COVID-19 severity to Neanderthals, the New York Times reports.

In PNAS this week: soil bacteria-derived small molecules affect centrosomal protein, microfluidics approach for capturing circulating tumor cells, and more.