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The researchers reported that targeting HDAC4 in the patient-derived neurons appeared to correct the expression of genes that differed in the disease state.

This Week in Nature

In Nature this week: approach to identify genetic variants that affect trait variability, application of read clouds to microbiome samples, and more.

This Week in Nature

In Nature this week: full UK Biobank dataset published, shark genomes give glimpse into cartilaginous fish evolution, and more.

The UK Biobank has collected genotyping, medical, and other phenotypic data on nearly 500,000 individuals, which it says will fuel additional studies.

Participants aim to use predictive modeling to better understand epigenetic mechanisms, while encouraging the development of new technologies and therapies.

ScienceInsider reports that universities may be worse than drug companies at reporting clinical trial results.

The virus emerged in northeastern Brazil and spread southward, though was transmitted through the sylvan cycle, the researchers' analysis showed.

Public health microbiologists are forging ahead with WGS, even as others caution that it may not yet be ready for such a role, said speakers at ASM Microbe 2018.

Diagnostic WGS will be centralized and performed at the same Genomics England facility used in the 100,000 Genomes Project.

Researchers sequenced 61 Zika virus genomes isolated from patients in the region to reconstruct viral movements.

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US National Institutes of Health Director Francis Collins says he will avoid male-only speaker panels.

Two patients fell ill, and one subsequently died, following a fecal microbiome transplant that harbored multi-drug-resistant bacteria, according to the New York Times.

Technology Review reports that eGenesis is testing whether organs from genetically modified pigs can be transplanted into monkeys.

In Science this week: almond reference genome, and more.