With single-cell genome sequencing, recombination assays, and other approaches in mouse cells, researchers identified factors affecting DNA crossover.
A genome-wide association study involving more than 12,300 carpal tunnel syndrome patients and controls from the UK Biobank led to 16 genetic loci.
Researchers from the University of Oxford have devised an approach to quickly search viral and bacterial genomes, according to the Atlantic.
Researchers have found that most genome-wide association study participants hail from just three countries, leading them to call for increased diversity.
A GWAS meta-analysis involving 10,074 PCOS cases revealed three new and 11 known risk loci, along with a relatively consistent genetic architecture among cases.
Using UK Biobank data, the researchers uncovered new variants in MC1R, as well as eight other variants, that influence whether someone has red hair.
The researchers reported that targeting HDAC4 in the patient-derived neurons appeared to correct the expression of genes that differed in the disease state.
In Nature this week: approach to identify genetic variants that affect trait variability, application of read clouds to microbiome samples, and more.
In Nature this week: full UK Biobank dataset published, shark genomes give glimpse into cartilaginous fish evolution, and more.
The UK Biobank has collected genotyping, medical, and other phenotypic data on nearly 500,000 individuals, which it says will fuel additional studies.
The US Department of Justice has proposed a rule change to enable DNA to be collected from migrants, the Associated Press reports.
Bernard Fisher, a surgeon who changed how breast cancer is treated, has died at 101, the New York Times reports.
A Washington Post columnist writes that she is skeptical about DNA-based diets.
In PNAS this week: recurrent inactivation of DEPDC5 in gastrointestinal stromal tumors, taxonomic reliability of GenBank sequences, and more.