Using UK Biobank data, the researchers uncovered new variants in MC1R, as well as eight other variants, that influence whether someone has red hair.
The researchers reported that targeting HDAC4 in the patient-derived neurons appeared to correct the expression of genes that differed in the disease state.
In Nature this week: approach to identify genetic variants that affect trait variability, application of read clouds to microbiome samples, and more.
In Nature this week: full UK Biobank dataset published, shark genomes give glimpse into cartilaginous fish evolution, and more.
The UK Biobank has collected genotyping, medical, and other phenotypic data on nearly 500,000 individuals, which it says will fuel additional studies.
Participants aim to use predictive modeling to better understand epigenetic mechanisms, while encouraging the development of new technologies and therapies.
ScienceInsider reports that universities may be worse than drug companies at reporting clinical trial results.
The virus emerged in northeastern Brazil and spread southward, though was transmitted through the sylvan cycle, the researchers' analysis showed.
Public health microbiologists are forging ahead with WGS, even as others caution that it may not yet be ready for such a role, said speakers at ASM Microbe 2018.
Diagnostic WGS will be centralized and performed at the same Genomics England facility used in the 100,000 Genomes Project.
The Washington Post reports on a Federal Bureau of Investigation plan to place rapid DNA analyzers at booking stations around the country.
In an editorial, officials from scientific societies in the US and China call for the international community to develop criteria and standards for human germline editing.
The US National Institutes of Health is to review studies that have received private support for conflicts of interest, according to the New York Times.
In Science this week: the PsychENCODE Consortium reports on the molecular mechanisms of neuropsychiatric disorders, and more.