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This Week in Science

In Science this week: whole-genome sequencing of single sperm cells, and more.

With single-cell genome sequencing, recombination assays, and other approaches in mouse cells, researchers identified factors affecting DNA crossover.

A genome-wide association study involving more than 12,300 carpal tunnel syndrome patients and controls from the UK Biobank led to 16 genetic loci.

Speed Search

Researchers from the University of Oxford have devised an approach to quickly search viral and bacterial genomes, according to the Atlantic.

All Very Similar

Researchers have found that most genome-wide association study participants hail from just three countries, leading them to call for increased diversity.

A GWAS meta-analysis involving 10,074 PCOS cases revealed three new and 11 known risk loci, along with a relatively consistent genetic architecture among cases.

Using UK Biobank data, the researchers uncovered new variants in MC1R, as well as eight other variants, that influence whether someone has red hair.

The researchers reported that targeting HDAC4 in the patient-derived neurons appeared to correct the expression of genes that differed in the disease state.

This Week in Nature

In Nature this week: approach to identify genetic variants that affect trait variability, application of read clouds to microbiome samples, and more.

This Week in Nature

In Nature this week: full UK Biobank dataset published, shark genomes give glimpse into cartilaginous fish evolution, and more.

Pages

Researchers representing scientists and students of Chinese descent voice their concerns about recent US policies and rhetoric.

Wired reports that researchers have shown they could reprogram a DNA-based computer.

Researchers say increased diversity in genomic studies will benefit all, PBS NewsHour reports.

In Science this week: whole-genome sequencing of single sperm cells, and more.