University of Montreal
Blood Cell Traits Linked to Individual Loci, Polygenic Contributors in International Studies
Two new papers have identified thousands of genetic loci with ties to more than two-dozen blood cell traits in individuals from up to five ancestry groups.
Polygenic Risk Scores Predict Heart Disease in French-Canadian Cohort
The two genome-wide scores to predict coronary artery disease risk, which were developed using UK Biobank data, were also valid in French-Canadians.
Proteogenomic Approach Identifies Candidate Tumor-Specific Antigens for Immunotherapies
Researchers were able to identify 40 tumor-specific antigens within two mouse cancer cell lines and seven human primary tumors using this approach.
Rare Variants Play Outsized Role in Human Height
A meta-analysis of hundreds of thousands of individuals led to several dozen rare or low-frequency variants with relatively pronounced effects on height.
Inuit Gut Microbiome Shares Features With Gut Communities From Westernized, Urban Center
A phylogenetic analysis of gut microbial communities in the Inuit population revealed broad similarities to gut microbiomes from individuals in the city of Montreal.