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Using transcriptomic, metabolomic, metagenomic, and other data types, a team identified purine metabolism as a potential target for intervention.

In PNAS this week: concerns regarding proposed SARS-CoV-2 phylogenetic network, adaptations that help Enterococcus establish infections, and more.

The screen, which multiplexes Cas9 and Cas12a, could be used for functional analysis of large genomic regions in mammalian cells, the researchers said.

In PNAS this week: gene expression profiles of adipocyte subtypes, computational approach for improving plant expressome analysis, and more.

Researchers have sequenced the zebra mussel genome, which they say could give insight into how to control the invasive species, says the Star Tribune.

The money is being provided under three Genome Canada funding competitions in partnership with the Canadian federal government and other groups.

Hmong and Karen immigrants to the US quickly lost diversity in their microbiomes and experienced shifts in the microbes present in their guts.

The firm will use the grant to accelerate the commercialization of synthetic DNA standards and algorithms licensed from the University of Minnesota.

In PLOS this week: links between gut microbiome and colorectal cancer mutations, targeted sequencing uncovers genetic susceptibilities to epilepsy in Koreans, and more.

In PLOS this week: de novo mutations in epileptic encephalopathy, sequencing analysis of aromatic rice, and more.

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Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.