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In PLOS this week: analysis of polygenic risk scores for skin cancer, chronic pain GWAS, and more.

The Genes for Good Project has engaged 80,000 Facebook users via its online application and genotyped 27,000 people to date.

Keytruda and Ibrance demonstrate activity in molecularly defined populations, while a new cohort will explore Gilotrif in tumors with NRG1 fusions.

The University of Michigan researchers aim to commercialize the Hydro-Seq microfluidic platform, which isolates and prepares single circulating tumor cells for RNA sequencing.  

With exome sequences from tens of thousands of T2D cases or controls from five ancestral groups, researchers identified genes that are frequently impacted by rare T2D-linked variants.

The new technique, enabled by enzymatic library preparation and a tight bioinformatics pipeline, could have applications in liquid biopsy.

Clinical researchers at AACR discussed a wide range of approaches focusing on several different potential use-cases in the detection or assessment of early cancers.

Some 43 percent of new mothers and 23 percent of new fathers leave full-time employment in STEM in the years after having a child, Science Careers says.

Researchers used exome capture RNA sequencing to come up with a collection of circRNAs in dozens of cancer types, including proposed prostate cancer markers.

This Week in PNAS

In PNAS this week: Fanconi anemia protein role in ribosome biogenesis, small interfering RNAs in A. thaliana seeds development, and more.

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The Hill reports President Donald Trump issued an executive directing federal agencies to cut the number of board and advisory committees they have.

The New York Times reports that researchers are combining tools to more quickly develop crops to feed a growing population and cope with shifting climates.

Scientists in Canada are looking to the UK's plan to sequence children with rare conditions for inspiration, the National Post reports.

In PNAS this week: copy number changes arose during polar bear evolution, genomic and transcriptomic analysis of the Siberian hamster, and more.