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University of Michigan

In Nature this week: residual protein expression uncovered for a third of CRISPR targets, and more.

Cytek believes the updated Aurora platform, which the company says can resolve 40 colors, may curb errors and costs for spectral analysis.

With exome sequences for tens of thousands of Finns, researchers identified deleterious variants linked to dozens of clinically relevant quantitative traits.

In PLOS this week: analysis of polygenic risk scores for skin cancer, chronic pain GWAS, and more.

The Genes for Good Project has engaged 80,000 Facebook users via its online application and genotyped 27,000 people to date.

Keytruda and Ibrance demonstrate activity in molecularly defined populations, while a new cohort will explore Gilotrif in tumors with NRG1 fusions.

The University of Michigan researchers aim to commercialize the Hydro-Seq microfluidic platform, which isolates and prepares single circulating tumor cells for RNA sequencing.  

With exome sequences from tens of thousands of T2D cases or controls from five ancestral groups, researchers identified genes that are frequently impacted by rare T2D-linked variants.

The new technique, enabled by enzymatic library preparation and a tight bioinformatics pipeline, could have applications in liquid biopsy.

Clinical researchers at AACR discussed a wide range of approaches focusing on several different potential use-cases in the detection or assessment of early cancers.

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Forensic genetic firm Verogen has bought the genetic genealogy site GEDmatch.

Researchers have 3D-printed plastic bunnies that encase the information needed to make more such bunnies in DNA, according to Discover magazine.

Dan Rather, the former CBS Evening News anchor and executive producer of a new documentary, writes at the Guardian that everyone needs to know about CRISPR.

In PNAS this week: analysis of FOXA1 upregulation in ER-positive breast cancer, gene editing to correct recessive dystrophic epidermolysis bullosa, and more.