At least half a dozen cancer phenotypes showed significant associations with GWAS variant-based polygenic risk scores in a new phenome-wide association study.
A study of more than 5,000 breast cancer patients found that multi-gene sequencing has rapidly replaced BRCA1/2-only tests, resulting in better pathogenic variant detection but also higher VUS rates.
The firm has developed microbubbles that bind to target molecules based on surface antibodies.
Investigators from several centers outlined tumor features, treatment strategies, and clinical trial classifications coming from tumor-germline clinical sequencing programs.
Physicians and prostate cancer patients are beginning to turn to genomic tests to guide treatment decisions, according to the Wall Street Journal.
The researchers said their study uncovered an unmet need that could be addressed by changing how genetic counseling is included in clinical practice.
With a two-stage atrial fibrillation GWAS, researchers took a crack at untangling the pathways, regulatory features, and tissue types contributing to the heart condition.
Michigan researchers report that the lncRNA THOR might have a key role in cancer development.
Investigators used sequencing, phylogenetics, and epidemiology to retrace transmission during a 2008 outbreak of carbapenem-resistant Klebsiella pneumoniae.
Participants in the pilot will begin developing the capabilities required for the planned data commons, including making data transparent and interoperable.
Researchers have sequenced the northern white rhinoceros to gauge whether it could be brought back from the edge of extinction, the New York Times reports.
Bavaria expands its forensic genetic analyses to include DNA phenotyping, raising discrimination concerns.
Tufts University researchers found a role for miRNA in transmitting stress between generations, the Economist reports.
In Science this week: gut microbiome influences liver cancer growth, spread; and more.