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University Medical Center Utrecht

Tumor genomes from almost 2,400 patients with metastatic cancer revealed a range of somatic alterations, providing a foundation for clinical sequencing efforts.

The early-stage genomics-based trials suggest tumor sequence can be informative for late-stage cancers, as an ESMO group seeks clinically meaningful translation.

Cyclomics, a 2018 spinout from University Medical Center Utrecht, is testing its assay for treatment response and recurrence monitoring in head and neck cancer.

The new European initiative promises to deliver multiple new tests and methods for improving the treatment of breast cancer and rectal cancer.

Philips and its partners aim to combine liquid biopsy with magnetic resonance imaging to enable personalized cancer treatment.

Backed by €19 million in EU funding, the initiative, called [email protected], will create a research platform that could change the way cardiovascular diseases are diagnosed and treated.

In Genome Research this week: computational method for detecting repeat expansions, approach to find mosaic structural changes, and more.

The researchers particularly highlighted C21orf2 and NEK1, which are involved in cilial and mitochondrial function.

While unsolicited germline findings in cancer patients were rare, they made the researchers reevaluate their pre-test counseling, informed consent, and reporting process.

Using whole-exome sequencing early in the diagnostic process could save $3,500 on average in patients who obtain a diagnosis from it and $1,700 in patients who do not.

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Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.