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University Medical Center Utrecht

Infant Microbiome Development Traced to Multiple Maternal Transmission Sources

Researchers assessed maternal and infant samples over time, uncovering a similar proportion of maternal microbes in microbiomes from cesarean or vaginal birth babies.

Inherited Cancer Risk Detected in Significant Subset of Wilms Tumor Cases

Researchers detected hereditary cancer susceptibility in around one-third of the Wilms tumor cases profiled in the Netherlands.

Metastatic Tumor Profiles Lead to Potential Treatment Targets

Tumor genomes from almost 2,400 patients with metastatic cancer revealed a range of somatic alterations, providing a foundation for clinical sequencing efforts.

Netherlands Drug Repurposing, Tumor Profiling Trial Results Reported at ESMO

The early-stage genomics-based trials suggest tumor sequence can be informative for late-stage cancers, as an ESMO group seeks clinically meaningful translation.

Dutch Startup Cyclomics Developing Liquid Biopsy Assay Using Nanopore Sequencing
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Cyclomics, a 2018 spinout from University Medical Center Utrecht, is testing its assay for treatment response and recurrence monitoring in head and neck cancer.

Dec 6, 2017

Philips-Led European Oncology Project Integrating Molecular Testing, Liquid Biopsy, Medical Imaging
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Nov 27, 2017

Philips, Partners Win €6.3M Grant to Develop Personalized Cancer Treatment Approach

Nov 27, 2017

European Consortium Aims to Deliver New Tests, Therapies for Cardiovascular Diseases
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Jul 25, 2016

Novel ALS Susceptibility Variants Uncovered in Pair of Studies

Apr 22, 2016

Secondary Findings in Cancer Patients Spur Dutch Team to Rethink Consent, Reporting Options
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Feb 5, 2016

Dutch Study Finds Exome Sequencing Could Cut Costs for Dx in Children With Intellectual Disability

Jan 25, 2016

Dutch Researchers Annotate Cis-Regulatory Elements in Primate Brains

Mar 19, 2015

Researchers Discover Chromothripsis in Healthy Mothers of Children with Congenital Abnormalities

Aug 3, 2012

Dutch Researchers Head SU2C Tumor Profiling Study

Jul 10, 2012

As More Labs Introduce Array-based Prenatal Dx Tests, Debate Rages over Indication, Platform Choice
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Oct 11, 2011

BGI Partners with Utrecht University, University Medical Center Utrecht
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Oct 10, 2011

BGI, Utrecht Ink Partnership

Jul 14, 2009

Researchers Beware: Sequencing-Based DGE Profiling of Small RNA is Biased, Study Says
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The Scan

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.

Algorithm Teases Out Genetic Ancestry in Individuals at Biobank Scale

Researchers develop an algorithm known as Rye to tease apart ancestry fractions in admixed individuals at a biobank-scale, applying it to 488,221 UK Biobank participants in Nucleic Acids Research.

Multi-Ancestry Analysis Highlights Comparable Common Variants at Complex Trait-Linked Loci

Researchers in Nature Genetics examine common variants implicated in more than three dozen conditions, estimating genetic effect similarities across ancestry tracts in admixed individuals.

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.