University Medical Center Utrecht
Developed by researchers in the Netherlands, the workflow can rapidly classify deadly CNS tumors within 90 minutes using methylation signals.
Pan-Cancer Genome Analyses Reveal Metastatic, Immune Escape Patterns
With whole-genome sequencing on more than 7,100 primary or metastatic tumors, researchers untangled disease progression, treatment resistance, and immune escape features.
Infant Microbiome Development Traced to Multiple Maternal Transmission Sources
Researchers assessed maternal and infant samples over time, uncovering a similar proportion of maternal microbes in microbiomes from cesarean or vaginal birth babies.
Inherited Cancer Risk Detected in Significant Subset of Wilms Tumor Cases
Researchers detected hereditary cancer susceptibility in around one-third of the Wilms tumor cases profiled in the Netherlands.
Metastatic Tumor Profiles Lead to Potential Treatment Targets
Tumor genomes from almost 2,400 patients with metastatic cancer revealed a range of somatic alterations, providing a foundation for clinical sequencing efforts.