University of Manchester Type 2 Diabetes Multi-Ancestry GWAS Enables Risk Prediction Across Populations With data for more than 180,800 cases and some 1.2 million controls, researchers found hundreds of genetic risk loci and developed multi-ancestry risk scores. Kidney Omics Study Sheds Light on Blood Pressure Mechanisms Combining genomic, transcriptomic, and epigenomic profiles from human kidneys with GWAS results, investigators discovered blood pressure targets and regulators. Endometrial Cancer Study Identifies 24 Variants Linked to Disease Predisposition University of Manchester and University of Cambridge researchers found SNPs in genes involved in cell survival, estrogen metabolism, and transcriptional control. Gene Panel Finds Pathogenic Variants Missed by Standard Tests in 5 Percent of Familial Cancer Cases The researchers profiled 44 cancer-related genes in 191 individuals with familial breast cancer, colorectal cancer, or other forms of early-onset cancer. New Early Cancer Detection Alliance to Trial Bevy of New Technologies and Tests Premium The number of technologies to be assessed is vast, and ranges from liquid biopsies and molecular imaging to immunohistochemistry and RNA-seq. Oct 7, 2019 Lung Cancer Studies From TRACERx Consortium Explore How Tumor Cells Evolve Oct 7, 2019 Prostate Cancer Methylation Levels Linked to Regulatory Variants in Germline Aug 23, 2019 Genedrive Prepping for UK Commercial Launch of PGx Test for Neonatal Hearing Loss Premium May 23, 2019 Qiagen-Backed Firm Apis Assay Technologies Launches in Manchester Innovation Hub Feb 25, 2019 Insomnia Studies Reveal New Risk Loci, Related Conditions Dec 3, 2018 UV-Induced DNA Damage Signature Linked to Better Melanoma Outcomes Sep 18, 2018 Type 1 Diabetes, Rheumatoid Arthritis Causal Variants Defined by Fine Mapping, Functional Analyses Sep 4, 2018 Identical Twins With, Without Rheumatoid Arthritis Have Differentially Variable DNA Methylation Aug 3, 2018 Variant Linked to BRCA1 Silencing Found in Two Families Affected by Breast, Ovarian Cancer Nov 20, 2017 Rare Bacterial Taxa May Play Outsize Role in Soil Microbiome Structure, Study Suggests Aug 3, 2017 Lynch Syndrome Analysis Suggests Patients Can Be Stratified for Surveillance Based on Mutation Type Nov 21, 2016 Copy Number Profiles Classify Lung Cancer Patients as Sensitive or Resistant to Therapy Jul 5, 2016 New U of Manchester Center Looks to Grow Proteomics for Diagnostics, Drug Discovery Premium May 25, 2016 Angle Plans £10.2M Placement Apr 20, 2016 Burgeoning Radiogenomics Efforts Aim to Improve Cancer Therapy, Reduce Toxicities Premium Sep 8, 2015 AstraZeneca to Invest $17.7M in University of Manchester-led Oncology Bioinformatics Effort May 11, 2015 BBSRC Funds UK-China Metabolomics Data-Sharing Collaboration Apr 28, 2015 Study Finds Markers of Rheumatoid Arthritis Risk Also Predict Severity and Drug Response Premium Apr 23, 2015 CRUK Manchester Institute Joins European Consortium Validating Blood-based Cancer Biomarkers Oct 23, 2014 U of Manchester Receives $38.5M for Research Using Omics, Other Technologies Load More Breaking News Guardant Health Files Motions to Dismiss, Change Venue in Illumina Patent Lawsuit In Brief This Week: SQI Diagnostics, T2 Biosystems, Enhanc3D, QuidelOrtho, More Illumina, Precision Health Research Singapore Partner for 100K Genomes Population Study 23andMe Fiscal Q4 Revenues Increase 14 Percent Local Coverage Determinations Roundup: Castle Bio, SkylineDx Ancient Genome Sequence Provides Look at Ancestry for Individual Who Perished at Pompeii The Scan Science Papers Present Way to Molecularly Classify Prostate Cancer, Saliva-Based SARS-CoV-2 Test, More In Science this week: approach to molecularly classify prostate tumors, saliva-based test for SARS-CoV-2, and more. Billion-Dollar Diversity Initiative The Howard Hughes Medical Institute is now accepting applications for its new $1.5 billion initiative to boost the diversity of the scientific workforce. Biotech Co-Founder Arrested A co-founder of a Los Angeles-based biotech company has been arrested in connection with a murder-for-hire scheme, according to Endpoint News. Return of the Tasmanian Tiger The Washington Post reports that a team in Australia is working to bring the thylacine back from extinction.