University of Manchester Kidney Omics Study Sheds Light on Blood Pressure Mechanisms Combining genomic, transcriptomic, and epigenomic profiles from human kidneys with GWAS results, investigators discovered blood pressure targets and regulators. Endometrial Cancer Study Identifies 24 Variants Linked to Disease Predisposition University of Manchester and University of Cambridge researchers found SNPs in genes involved in cell survival, estrogen metabolism, and transcriptional control. Gene Panel Finds Pathogenic Variants Missed by Standard Tests in 5 Percent of Familial Cancer Cases The researchers profiled 44 cancer-related genes in 191 individuals with familial breast cancer, colorectal cancer, or other forms of early-onset cancer. New Early Cancer Detection Alliance to Trial Bevy of New Technologies and Tests Premium The number of technologies to be assessed is vast, and ranges from liquid biopsies and molecular imaging to immunohistochemistry and RNA-seq. Lung Cancer Studies From TRACERx Consortium Explore How Tumor Cells Evolve Researchers from the TRACERx consortium analyzed blood and tumor samples to tease out features of lung cancers that are more likely to recur. Oct 7, 2019 Prostate Cancer Methylation Levels Linked to Regulatory Variants in Germline Aug 23, 2019 Genedrive Prepping for UK Commercial Launch of PGx Test for Neonatal Hearing Loss Premium May 23, 2019 Qiagen-Backed Firm Apis Assay Technologies Launches in Manchester Innovation Hub Feb 25, 2019 Insomnia Studies Reveal New Risk Loci, Related Conditions Dec 3, 2018 UV-Induced DNA Damage Signature Linked to Better Melanoma Outcomes Sep 18, 2018 Type 1 Diabetes, Rheumatoid Arthritis Causal Variants Defined by Fine Mapping, Functional Analyses Sep 4, 2018 Identical Twins With, Without Rheumatoid Arthritis Have Differentially Variable DNA Methylation Aug 3, 2018 Variant Linked to BRCA1 Silencing Found in Two Families Affected by Breast, Ovarian Cancer Nov 20, 2017 Rare Bacterial Taxa May Play Outsize Role in Soil Microbiome Structure, Study Suggests Aug 3, 2017 Lynch Syndrome Analysis Suggests Patients Can Be Stratified for Surveillance Based on Mutation Type Nov 21, 2016 Copy Number Profiles Classify Lung Cancer Patients as Sensitive or Resistant to Therapy Jul 5, 2016 New U of Manchester Center Looks to Grow Proteomics for Diagnostics, Drug Discovery Premium May 25, 2016 Angle Plans £10.2M Placement Apr 20, 2016 Burgeoning Radiogenomics Efforts Aim to Improve Cancer Therapy, Reduce Toxicities Premium Sep 8, 2015 AstraZeneca to Invest $17.7M in University of Manchester-led Oncology Bioinformatics Effort May 11, 2015 BBSRC Funds UK-China Metabolomics Data-Sharing Collaboration Apr 28, 2015 Study Finds Markers of Rheumatoid Arthritis Risk Also Predict Severity and Drug Response Premium Apr 23, 2015 CRUK Manchester Institute Joins European Consortium Validating Blood-based Cancer Biomarkers Oct 23, 2014 U of Manchester Receives $38.5M for Research Using Omics, Other Technologies Jun 16, 2014 Whipworm Genomes Offer Peek at Parasitic Interactions, Potential Anti-inflammatory Applications Load More Breaking News Singular Genomics Systems Reports No Revenues, Increased Net Loss for Q2 Burning Rock Biotech, Impact Therapeutics Partner on CDx for PARP Inhibitor Senaparib Gene Editing Analysis Firm SeQure Dx Closes $17.5M Series A Funding Round Resolve Biosciences, Zeiss Partner to Enhance Spatial Biology Imaging Tech EliTechGroup Obtains CE Mark for Saliva Use With SARS-CoV-2 Test Waters Q2 Revenues Up 31 Percent The Scan And Back The New York Times reports that missing SARS-CoV-2 genome sequences are back in a different database. Lacks Family Hires Attorney A lawyer for the family of Henrietta Lacks plans to seek compensation from pharmaceutical companies that have used her cancer cells in product development, the Baltimore Sun reports. For the Unknown The Associated Press reports that family members are calling on the US military to use new DNA analysis techniques to identify unknown sailors and Marines who were on the USS Arizona. PLOS Papers on Congenital Heart Disease, COVID-19 Infection Host MicroRNAs, Multiple Malformation Mutations In PLOS this week: new genes linked to congenital heart disease, microRNAs with altered expression in COVID-19, and more.