University of Manchester
Kidney Omics Study Sheds Light on Blood Pressure Mechanisms
Combining genomic, transcriptomic, and epigenomic profiles from human kidneys with GWAS results, investigators discovered blood pressure targets and regulators.
Endometrial Cancer Study Identifies 24 Variants Linked to Disease Predisposition
University of Manchester and University of Cambridge researchers found SNPs in genes involved in cell survival, estrogen metabolism, and transcriptional control.
Gene Panel Finds Pathogenic Variants Missed by Standard Tests in 5 Percent of Familial Cancer Cases
The researchers profiled 44 cancer-related genes in 191 individuals with familial breast cancer, colorectal cancer, or other forms of early-onset cancer.
The number of technologies to be assessed is vast, and ranges from liquid biopsies and molecular imaging to immunohistochemistry and RNA-seq.
Lung Cancer Studies From TRACERx Consortium Explore How Tumor Cells Evolve
Researchers from the TRACERx consortium analyzed blood and tumor samples to tease out features of lung cancers that are more likely to recur.