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University of Manchester

The company, which is also backed by Health Innovation Manchester, aims to expedite the commercialization of biomarkers into new diagnostic tests.

Using data for more than a million individuals with or without insomnia, two independent research teams tracked down associated risk loci and explored their functional effects.

A handful of exposures to ultraviolet radiation was enough to induce the melanoma-associated signature within a mouse model.

Researchers used fine mapping and other approaches to prioritize proposed coding and non-coding causal variants at rheumatoid arthritis- and type 1 diabetes-linked loci.

These differentially variable positions appear to implicate stress response in rheumatoid arthritis development and possibly in other autoimmune conditions.

A heterozygous variant upstream of the BRCA1 translation start site was uncovered in all individuals in these two families with hypermethylated BRCA1 promoters.

In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.

Analysis of ancient DNA from mummies known as the Two Brothers finds they are half-brothers, according to Science News.

An integrated analysis of 30 soil microbiome datasets suggests that common bacterial taxa may be less useful ecological indicators compared to much rarer taxa.

Clearer Risk

The Guardian reports that a new genetic risk test for breast cancer may give clearer risk estimates.

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Researchers uncovered the HIV virus within a tissue sample collected in 1966, the Atlantic reports.

Nature News reports there are a handful of clinical trials underway to evaluate vaginal microbiome seeding of newborns born via caesarian section.

The Washington Post writes that humans may have contributed to the extinction of cave bears some 20,000 years ago.

In PLOS this week: gene variant may protect against trypanosomiasis, GLIS3 role in type 2 diabetes, and more.