University of Manchester

Researchers used fine mapping and other approaches to prioritize proposed coding and non-coding causal variants at rheumatoid arthritis- and type 1 diabetes-linked loci.

These differentially variable positions appear to implicate stress response in rheumatoid arthritis development and possibly in other autoimmune conditions.

A heterozygous variant upstream of the BRCA1 translation start site was uncovered in all individuals in these two families with hypermethylated BRCA1 promoters.

This Week in PLOS

In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.

Analysis of ancient DNA from mummies known as the Two Brothers finds they are half-brothers, according to Science News.

An integrated analysis of 30 soil microbiome datasets suggests that common bacterial taxa may be less useful ecological indicators compared to much rarer taxa.

Clearer Risk

The Guardian reports that a new genetic risk test for breast cancer may give clearer risk estimates.

In a retrospective cohort study of Lynch syndrome patients, researchers found that cancer onset varied both by which gene was mutated and how it was altered.

A new analysis finds that collagen thought to have belonged to Tyrannosaurus rex was likely contamination, the International Business Times reports.

University of Manchester researchers describe their design for DNA computing, according to Popular Mechanics.

Pages

The New York Times and ProPublica look into the close relationship between a startup and Memorial Sloan Kettering Cancer Center.

Yahoo News reports millions of dollars are being transferred from NIH, CDC, and other programs to pay for the housing of detained undocumented immigrant children.

In Science this week: in vitro generation of human reproductive cells, and more.

Researchers gave a handful of octopuses MDMA to find that they too act more social on the drug, Gizmodo reports.