University of Groningen Microbial Fingerprints, Health Insights Gleaned From Individual Gut Microbiome Dynamics With gut microbiome data for individuals sampled four years apart, researchers saw stable and unstable gut microbial species, including those linked to host phenotypes. Genetic Variants Influence Cardiac Features Captured By Electrocardiograms, Study Finds The University of Groningen-led team further uncovered variants associated with risk of dilated cardiomyopathy. CRISPR Researchers Use Cas12a to Develop Multiplex Genome Engineering Platform The team used this system to perform orthogonal and multiplexed genome engineering of endogenous targets using up to 25 individual CRISPR RNAs. Single-Cell Lung Atlases Reveal New Cell Types, Asthma-Related Alterations With RNA sequence data on thousands of individual lung cells, researchers fleshed out new and known cell clusters, before digging into cell state and cellular interaction changes in asthma. Inflammatory Bowel Disease, Irritable Bowel Syndrome Show Differences in Gut Microbiomes Research suggests gut microbe representation, abundance, and function may provide clues for diagnosing Crohn's disease, ulcerative colitis, and irritable bowel syndrome. Nov 1, 2018 Chronic Infection Genetic Risk Loci Point to Immune, Metabolic Pathways Sep 24, 2018 Genetics, Gut Microbes Linked to Blood Levels of Cardiovascular Disease-Related Proteins Jun 27, 2018 Lifestyle, Genetics Independently Predict Cardiovascular Disease, Diabetes Risk Mar 1, 2018 Heart Rate GWAS Provides Insight on Exercise Response, Recovery Oct 31, 2016 Resting Heart Rate Linked to Overall Mortality Through Dozens of Genetic Loci Oct 7, 2016 Haplotype-Resolved Structural Variant Map Highlights Complexity of Human Genome Sep 23, 2016 Strand-Seq Analytical Pipeline Developed for Direct Haplotyping Premium Jun 3, 2016 Tumor Karyotype Heterogeneity May Predict Outcomes, Inform Treatment Options, Dutch Team Finds Premium May 19, 2016 CRISPR/Cas9 Takes Root in Core Facilities Worldwide Premium May 18, 2016 Netherlands Considers Patients' Preferences, Feasibility of Expanded Carrier Screening Premium Apr 28, 2016 Gut Microbiome Makeup Influenced by Medication Use, Other Factors Jan 27, 2016 Seagrass Genome Elucidates How Flowering Plant Re-adapted to Marine Environment Sep 9, 2013 Study Links GWAS Risk Loci to Distant Gene Expression Oct 27, 2009 In Some European Clinical Cytogenetic Labs, Arrays Have Become Primary Sample-Analysis Tool Premium Feb 4, 2009 Ovarian Cancer Prognostic Signature Reveals Key Pathways Breaking News Lunaphore Technologies, University of Bern Partner on Colorectal Cancer Study People in the News: New Appointments at Biocept, Novacyt, Centogene, Illumina, More In Brief This Week: Sophia Genetics, Twist Bioscience, Dante Labs, MGI, Codex DNA, More New Products Posted to GenomeWeb: SpeeDx, Bio-Techne, NuProbe, More DiaSorin Q2 Revenues Rise 20 Percent on SARS-CoV-2 Testing Demand Cepheid Gets $28M From BARDA for SARS-CoV-2 Tests The Scan Interfering With Invasive Mussels The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels. Participation Analysis A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports. Right Whales' Decline A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC. Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.