University of Groningen
Consortium Catalogs Variants Affecting Blood Gene Expression
Members of the eQTLGen Consortium turned to data for almost 31,700 individuals to define local and distant expression quantitative trait loci affecting gene expression in the blood.
Microbial Fingerprints, Health Insights Gleaned From Individual Gut Microbiome Dynamics
With gut microbiome data for individuals sampled four years apart, researchers saw stable and unstable gut microbial species, including those linked to host phenotypes.
Genetic Variants Influence Cardiac Features Captured By Electrocardiograms, Study Finds
The University of Groningen-led team further uncovered variants associated with risk of dilated cardiomyopathy.
CRISPR Researchers Use Cas12a to Develop Multiplex Genome Engineering Platform
The team used this system to perform orthogonal and multiplexed genome engineering of endogenous targets using up to 25 individual CRISPR RNAs.
Single-Cell Lung Atlases Reveal New Cell Types, Asthma-Related Alterations
With RNA sequence data on thousands of individual lung cells, researchers fleshed out new and known cell clusters, before digging into cell state and cellular interaction changes in asthma.