University of Geneva Metagenomics Enables Researchers to Uncover Pathogens, Drug Resistance Genes Metagenomics can help researchers and clinicians uncover sources of infectious disease and discern whether pathogens are resistant to antimicrobials. KRAS Mutations Revealed in Rare Vascular Brain Condition Researchers identified somatic KRAS mutations in affected tissue from more than 60 percent of people with sporadic arteriovenous malformations of the brain. Saphetor Adds Geneva University Hospitals to Client List for Variant Annotation Platform Premium HUG's genetic medicine arm will use Saphetor's software and variant knowledgebase in clinical projects focused on developmental and neurological disorders. Researchers Uncover Additional Drivers, Pathways Involved in Basal Cell Carcinoma An international team has uncovered roles for MYCN, PTPN14, and LATS1 mutations in the development and progression of skin basal cell carcinoma. Study of Twins Starts Unraveling Genetic, Environmental Contributors to Gene Regulation Sep 16, 2013 Widespread Variation Affects Regulation of Most Human Genes, Study Finds Dec 27, 2011 Melanoma Exome Sequencing Studies Find Recurrent Somatic Mutations in Kinase Family Sep 9, 2011 Swiss Team Explores Effects of Epistasis between Coding and Regulatory Variants Jun 7, 2011 Swiss Organizations Team up with Roche in Translational Research Mar 4, 2010 AB Sciex, U of Geneva to Collaborate on Mass Spec Workflows Jul 30, 2009 Team IDs Cell Type-Specific Expression Effects for Regulatory Variants Breaking News SARS-CoV-2 Variants of Concerns Evolved to Modify Host Immune Response, Multiomics Study Shows People in the News at GA4GH, Mercy BioAnalytics, Deepcell, One Biosciences New Products Posted to GenomeWeb: Clinical Microbiomics, Integra Biosciences, DNAstack, Bruker Angolan Namib Desert Population Analysis Uncovers New Ancestry Group With Deep Divergence Cedars-Sinai Sets Up $25M Single Cell Precision Medicine Center The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.