University of Edinburgh Epigenetic Study Finds Novel Associations Between DNA Methylation, Common Diseases Researchers analyzed DNA methylation patterns in whole blood samples from more than 18,000 Scottish individuals to find associations with common diseases. More Than Two Dozen Genetic Variants Linked to Severe COVID-19 in Meta-Analysis This meta-analysis of genome-wide association study data could help in the development of new therapeutics for critically ill COVID-19 patients. Infant Microbiome Development Traced to Multiple Maternal Transmission Sources Researchers assessed maternal and infant samples over time, uncovering a similar proportion of maternal microbes in microbiomes from cesarean or vaginal birth babies. Multiomic Study Points to New Colorectal Cancer Risk Contributors Researchers tracked down more than 100 new risk variants with a combination of genomic, transcriptomic, and methylation analyses, highlighting new and known risk pathways. Dyslexia GWAS Leads to Dozens of Risk Loci, Polygenic Risk Score A genome-wide association study that included more than a million cases or controls led to 42 genetic risk loci for dyslexia, along with a polygenic risk score. Jul 6, 2022 New Approach Improves Estimating Cancer Risk From Age-Related Clonal Hematopoiesis Mar 7, 2022 Whole-Genome Sequencing IDs New Host Genetic Variants Associated With Severe COVID-19 Feb 9, 2022 BioCaptiva Advancing Cell-Free DNA Isolation Device to Boost Liquid Biopsy Sensitivity Premium Jan 25, 2022 Scottish Startup Omecu Promises Secure, Fast Human Genome Analysis Premium Apr 29, 2021 New CRISPR Guide RNA Screen Helps Define Genetics of Spinal Cord Regeneration in Zebrafish Apr 8, 2021 GWAS Uncovers Sex-Based Differences in Genetic Origins of Chronic Pain Apr 6, 2021 Scottish Liquid Biopsy Startup BioCaptiva Raises £1M in Seed Funding Mar 17, 2021 Cancer Heritability Gene Set Expanded With Common Variant Analysis Jan 7, 2021 Pacific Biosciences HiFi Reads Drive Core Lab Business, High-Flying Stock Price Premium Dec 11, 2020 COVID-19 GWAS Leads to Immune Genes Linked to Severe Disease, Treatment Targets Nov 25, 2020 European Consortium Seeks to Develop Liquid Biopsy Test for Prostate, Testicular Cancer Premium Jul 20, 2020 New CRISPR Base Editors Induce Targeted DNA Transversions Premium Jun 15, 2020 U of Edinburgh Study to Use Consumer Genomics Data to Determine COVID-19 Genetic Risk May 12, 2020 Illumina, UK Agencies Partner on £28M Sequencing Study of COVID-19 Patients Dec 18, 2019 Nordic Project Aims to Investigate Link Between Mental Disorders and Cardiovascular Disease Premium Nov 8, 2019 Wellcome Sanger Institute Commits $11.8M to Darwin Tree of Life Project Oct 25, 2019 Helmsley Foundation Awards $13M in Grants for Gut Cell Atlas Oct 9, 2019 Single-Cell Transcriptome Atlas Gives Peek at Cell Interactions in Liver Cirrhosis Sep 3, 2019 Scottish Genetic Map Reflects Boundaries of Dark Age Kingdoms Feb 5, 2019 Depression GWAS Meta-Analysis Uncovers New Loci, Potential Drug Targets Load More Breaking News Compact Gene Editing Enzyme May Improve Success Rates of Gene Therapies People in the News at Veracyte, Invitae, Mount Sinai, InterVenn Biosciences, Applied BioCode, More New Products Posted to GenomeWeb: Qiagen, IDT, Revvity, Mission Bio, NRichDx, More FDA Releases Proposed Rule for Oversight of Laboratory-Developed Tests CStone Pharmaceuticals, Genetron Companion Diagnostic Receives NMPA Approval The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.