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University of Colorado

In Nucleic Acids Research this week: computational tool to uncover microbial traits from microbiome data, database of patient-derived xenograft from pediatric cancers, and more.

In PLOS this week: chromosomal integration of human herpesvirus 6, gene expression predictions across populations, and more.

Regeneron will sequence and annotate 450,000 exomes and pair the data with UCHealth patient records to advance drug discovery and precision medicine.

In Nucleic Acids Research this week: prostate cancer drugs' effect on androgen receptors, approach to gauge effects of epigenetic drugs, and more.

The precision medicine center at Colorado's UCHealth expects to add 100,000 participants annually and have 17 drug-gene pairs for pharmacogenomics this year. 

A preliminary analysis lends some support to covering NIPS for pregnancies beyond high-risk, and some payors have expanded coverage.  

 

In PLOS this week: missense variant linked to hereditary leukodystrophy in dogs, genetic variants associated with drug-induced interstitial lung disease, and more.

Wired reports that genetic variants may influence the effectiveness of hormonal birth control among some women.

These loci include a known asthma locus at 17q12-q21, but also loci at 8p23 and 8q24 that could be specific to asthma risk among individuals of African ancestry.

In Nucleic Acids Research this week: updated Aspergillus niger genome annotation, high-throughput sequencing strategy for profiling RNA structure, and more.

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UK Royal Statistical Society is organizing a working group to develop guidelines for assessing COVID-19 tests, the Guardian reports.

The Washington Post reports that the White House chief of staff has asked the US Food and Drug Administration to justify the stricter standards it is seeking for a coronavirus vaccine.

President Donald Trump's "good genes" comment raises eugenics concerns, CNN reports.

In PLOS this week: genetic analysis of tremor condition, analysis of a West and Central African tree used in traditional medicine, and more.