The goal of the project is two-fold: the exome sequencing portion of the study will look for genes that underlie the genesis of the disease, while whole-genome sequencing of patients' plasma will be used to look for patient-specific rearrangements that could be used as the basis for a test.
Based on findings from the Whitehall II prospective study, a team of University College London researchers concluded that two non-genetic risk models more accurately predicted type 2 diabetes risk than a genetic model based on 20 risk alleles.
Pfizer and UCL to develop stem-cell therapies for AMD; Clarient licenses breast cancer biomarkers from Indiana U; Nanosys and Harvard to outlicense nanowire IP; Luminex settles with SUNY and U of Illinois, and more …
Researchers in the Neuromuscular Disorder-Chip Consortium will use custom-designed NimbleGen Human CGH 12x135K microarrays and Human Sequence Capture 385K arrays to study the genetic underpinnings of a range of neuromuscular disorders.
Researchers from the Netherlands have uncovered a new gene expression signature linked to ovarian cancer survival that is providing hints about potential pathways of importance for the disease. But authors warn that using such signatures for guiding treatment may be a ways off.