University College London
Gastric Tissue Sequencing Study Reveals Recurrent Alterations, Precancerous Changes
By sequencing microdissected samples from individuals with or without gastric cancer, researchers characterized mutation rates and processes along the gastrointestinal tract.
Heart Failure GWAS Leads to New Risk Loci, Disease Subtype Insights
Researchers uncovered genetic contributors to heart failure, revealing multiorgan features and a reduced ejection fraction subtype that is particularly impacted by genetics.
TRACERx Lung Cancer Study Validates Prognostic Clonal Gene Expression Test
TRACERx researchers studied the 23-transcript ORACLE clonal expression biomarker, prospectively linking ORACLE risk classification to lung adenocarcinoma survival.
Investigators delved into the prevalence, genetic impacts, inheritance, and potential vulnerabilities of extrachromosomal DNA circles found in a subset of tumors.
Repeat Expansion Prevalence in Populations Higher Than Assumed, Study Finds
Researchers used genome sequence data for nearly 82,000 individuals to explore RED-related allele frequencies and features across populations.