University College London
TRACERx Lung Cancer Study Validates Prognostic Clonal Gene Expression Test
TRACERx researchers studied the 23-transcript ORACLE clonal expression biomarker, prospectively linking ORACLE risk classification to lung adenocarcinoma survival.
Investigators delved into the prevalence, genetic impacts, inheritance, and potential vulnerabilities of extrachromosomal DNA circles found in a subset of tumors.
Repeat Expansion Prevalence in Populations Higher Than Assumed, Study Finds
Researchers used genome sequence data for nearly 82,000 individuals to explore RED-related allele frequencies and features across populations.
Population Testing for BRCA1/2 Appears Cost-Effective in Younger Canadian Women
Using simulated data for 1 million women, researchers found that population-based BRCA1/2 testing would be cost-effective, particularly in 30-year-old women.
Study Points to Microbial Pioneers Behind Infant Gut Microbiome Assembly
Researchers identified three early gut microbiome community states and corresponding pioneer microbes with metagenomic data from the UK Baby Biome Study.