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University of Cincinnati

Using genome-wide association study, cell line, organoid, and other data, researchers tracked down polygenic contributors to drug-induced liver injury in hepatocytes.

In PLOS this week: Mycobacterium abscessus linked to gastric conditions, placental gene expression changes associated with preterm birth, and more.

The university will use the technology to screen blood samples for certain clinically actionable mutations in non-small cell lung cancer patients.

Researchers sequenced mothers who experienced preterm birth and found a possible role for steroid signaling in birth timing.

In PNAS this week: genome and transcriptome sequencing study of tobacco plants, molecular effects of cytochrome c oxidase mutations, and more.

In blood samples from infected individuals, a seven-gene signature apparently distinguishes between bacterial and viral culprits, a distinction important to antibiotic use.

Recently established biomedical informatics divisions at the hospital support projects like Bench-to-Bassinet and the Longitudinal Pediatric Data Resource.

Scientists will look for genetic causes of craniofacial asymmetries and loss of skin pigmentation in a cave-dwelling fish that could shed light on similar conditions in humans.

The goal is to identify patient-specific rearrangements in the primary tumor, and then check for the presence of that rearrangement in the patient's blood during treatment in order to determine tumor progression and monitor therapy response.

In the deal with the University of Cincinnati, Drug Discovery Center, Proteros will provide biotechnology and drug firms access to UC DCC's ultra-high throughput and high-content screening platform along with a library of more than 340,000 drug-like compounds.

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The Lancet has made changes to its peer-review process in response to its recent retraction of a COVID-19-related paper, Science reports.

The New York Times reports that a series of emails show how Department of Health and Human Services officials sought to silence the Centers for Disease Control and Prevention.

A new initiative aims to move Australia's genome sequencing labs onto one system, the Sydney Morning Herald reports.

In PLOS this week: recessive mutation tied to early-onset dilated cardiomyopathy, epigenetic analysis of lung adenocarcinoma, and more.