University of Chicago UChicago Testing Pharmacogenomics for Surgical Patients in Clinical Trial Premium Though more data is needed, the Center for Personalized Therapeutics is building the infrastructure for greater pharmacogenomic testing in the future. Studies Assess Tumor Aneuploidy to Guide Immunotherapy Treatment Results from two new studies suggest that tumor aneuploidy can provide an additional layer of information to help predict response to checkpoint blockade immunotherapy. Value of Diversity in Study Populations Highlighted at ASHG Premium Data from several presentations at the American Society of Human Genetics annual meeting demonstrated the benefits of using diverse ancestries in human genetic studies. Black Death Sequencing Study Reveals Impacts on Human Immune Evolution, Autoimmune Disease Researchers profiled DNA sequences in hundreds of ancient Europeans to find immune gene- and autoimmune disease-related variants under selection during the plague pandemic. Octopus, Squid Genome Assemblies Reveal Hallmarks of Cephalopod Evolution Researchers detected genome shuffling, gene expansions, and RNA editing changes in the cephalopod lineage using genome assemblies for three representatives. Mar 28, 2022 In AMIA Keynote, U of Chicago's Olopade Calls for More Diverse Data to Inform Precision Medicine Premium Dec 16, 2020 Dental Plaque Microbes Genetically More Similar to Those of Soil Than Nearby Tongue Dec 15, 2020 University of Chicago Program Aims to Improve Knowledge Transfer for PGx Testing Premium Dec 2, 2020 Epigenome Study Maps Hydroxymethylation Across Diverse Human Tissue Types Jul 29, 2020 Saliva Samples Slow to Catch On for Large-Scale Coronavirus Testing Premium Oct 25, 2019 Helmsley Foundation Awards $13M in Grants for Gut Cell Atlas Oct 15, 2019 Dart-seq Leads New Methods to Sequence Transcriptome Methylation Patterns Premium Jun 28, 2019 Influence of Some eQTLs During Development Is Short, But Could Have Lasting Effects Jun 3, 2019 Lynparza Delays Progression in Metastatic Pancreatic Cancer Patients With Germline BRCA Mutations Premium Dec 20, 2018 CancerIQ Seeks to Streamline Genetic Risk Screening Premium Nov 14, 2018 Bio-Rad Awarded $24M in 10x Genomics Patent Infringement Lawsuit Nov 8, 2018 Ancient DNA Sheds New Light on Human Migrations in the Americas Sep 18, 2018 Genomic Analysis of Present-Day Sardinians Shows Significant Influence From Neolithic Sources Aug 28, 2018 Study Links Food Preservative to Newly Detected Histone Modification Aug 22, 2018 Study of Breast Cancer Risk Genes in Nigerian Women Suggests Benefits of Genetic Screening May 4, 2018 Study Uncovers Curable Molecular Subtype of Colorectal Cancers Metastasized to Liver Mar 22, 2018 UVA-Led Group Using NCI Grant to ID Common Genetic Mechanisms Affecting Cancer Risk Premium Nov 6, 2017 NIH Awards $9M in Funding to Support Data Commons Pilot Phase Oct 25, 2017 Viral Evolution Data Improves Predictions of Flu Season Severity Oct 11, 2017 Studies Elucidate Impact of Genetic Variants on Gene Expression in Human Tissues Load More Breaking News Cancer Prognoses Informed by Module-Based Approach, Study Finds People in the News at Illumina, Centogene, BioSkryb New Products Posted to GenomeWeb: Bio-Rad, BD, Analytik Jena, BioMérieux Genetic Technologies to Raise A$5M in Direct Stock Offering In Brief This Week: SD Biosensors, Meridian, Oncocyte, Opko Health, GeneDx, More The Scan Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency. Circulating Tumor DNA Shows Potential as Biomarker in Rare Childhood Cancer A study in the Journal of Clinical Oncology has found that circulating tumor DNA levels in rhabdomyosarcoma may serve as a biomarker for prognosis. Study Recommends Cancer Screening for Dogs Beginning Age Seven, Depending on Breed PetDx researchers report in PLOS One that annual cancer screening for dogs should begin by age seven. White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.