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In Nature this week: the largest known collection of human genetic variants, and more.

In Genome Research this week: target-mismatched sgRNA in microbial genome editing, strategy to examine gene expression throughout the cell cycle, and more.

In Nature this week: comparative analyses of single-cell RNA sequencing protocols uncover differences between approaches, and more.

From the Depths

Researchers have sequenced the genome of the depth-dwelling giant squid.

For Later in Life

Bioethicists disagree with a research team's decision to allow the return of risk results for adult-onset conditions from a newborn sequencing project, according to Reuters.

The project is part of the Human Cell Atlas, an international effort to build reference maps of all human cell types using single-cell analysis.

A new sequencing-based method developed by Duke University's Kate Meyer is one of several that can detect RNA methylation without the use of antibodies.

In PNAS this week: induced "BRCAness" phenotype in non-small cell lung cancer, chemoproteomic profiling approach, and more.

In Genome Biology this week: analysis of colorectal cancer progression, secretion system used by Vibrio cholerae, and more.

In PLOS this week: networks of genes co-expressed in depression, role of minichromosome maintenance genes in lung adenocarcinoma, and more.

Pages

The Hill reports 17 states and the District of Columbia are suing over a new policy that would strip international students of their visas if they only attend classes online.

The editorial board of the Pittsburgh Post-Gazette says other lawmakers should take Florida's approach and provide additional protections against genetic discrimination.

Centers for Disease Control and Prevention employees call on the agency to label racism a public health crisis and examine its own policies, NPR reports.

In PNAS this week: genetic evidence for Inca resettlement, analysis of spermatogonial stem cell transcriptomes, and more.