University of Chicago
Mexican Population Studies Provide Ancestry, Complex Trait Clues
Teams teased out ancestry, allele frequency, imputation, and genetic risk variant profiles for populations using data from the Mexican Biobank and Mexico City Prospective Study.
Study Finds Mechanism Linking Noncoding Risk Locus, Disease-Related Cellular Phenotypes
Using ATAC-seq and CRISPR-Cas9 editing in cell lines, researchers established a link between a noncoding schizophrenia risk locus and cellular phenotypes.
Female-Specific Fat Distribution Gene, Regulatory Variant Emerge from Gene Expression Study
With transcriptome-wide association studies of BMI and waist-to-hip ratio adjusted for BMI, researchers began to untangle the genetics of fat distribution.
Guardant Health to Study Impact of Shield Blood Test on Colorectal Cancer Screening Compliance
University of Chicago investigators will offer the test to up to 2,400 patients who failed to complete recommended colon cancer screening and track the impact.
Though more data is needed, the Center for Personalized Therapeutics is building the infrastructure for greater pharmacogenomic testing in the future.