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University of Cape Town

An analysis of cases and controls from South Africa's Xhosa population pointed to private, damaging mutations in genes expressed in the brain.

Researchers sequenced and analyzed 169 Mycobacterium tuberculosis strains from people with and without HIV infections.

The supercomputer was used to identify genomic variants in some 300 deeply sequenced human samples for use in a planned bead-array-based genotyping chip.

The study describes an RNA expression signature unique to people who are likely to develop an active TB infection, which could help prevent it. 

Scientists from the University of Cape Town in South Africa have used nested PCR to discover that silica-based nucleic acid extraction products from Qiagen are contaminated with sequences linked to a purportedly novel virus previously identified in seronegative hepatitis patients

In a prospective study of children admitted to two Cape Town hospitals, researchers found that Cepheid MTB/RIF testing on two samples per child detected roughly twice as many tuberculosis cases as smear microscopy on induced sputum samples.

Researchers from the University of Cape Town and the Center for Proteomic and Genomic Research plan to use Affymetrix's DMET Plus product to investigate the prevalence of specific SNPs in southern African populations and the relationship of such traits with drug efficacy.

AstraZeneca has released its coronavirus vaccine trial protocol, according to the New York Times.

Time magazine looks into how liquid biopsies are changing cancer care.

According to the Guardian, more than 150 countries have signed on to a global SARS-CoV-2 vaccine plan.

In PNAS this week: similar muscle protein patterns across hypertrophic cardiomyopathy phenotypes, analysis of gene expression and brain anatomy in major depression, and more.