University of Cape Town
As organizers develop a plan to sequence 3 million genomes across Africa, bioinformaticians weigh the benefits and risks of such a large, diverse dataset.
Schizophrenia Exome Sequencing Study in South African Population Reveals Rare Mutations, Pathways
An analysis of cases and controls from South Africa's Xhosa population pointed to private, damaging mutations in genes expressed in the brain.
HIV Co-Infection Influences Evolutionary Selection Within TB Bacteria
Researchers sequenced and analyzed 169 Mycobacterium tuberculosis strains from people with and without HIV infections.
The supercomputer was used to identify genomic variants in some 300 deeply sequenced human samples for use in a planned bead-array-based genotyping chip.
International Research Team Develops Blood Test for Tuberculosis Risk Assessment
The study describes an RNA expression signature unique to people who are likely to develop an active TB infection, which could help prevent it.