University of Cambridge GE Healthcare Precision Oncology Pacts Focus on Cracking Data Silos, Improving Patient Outcomes Premium GE recently inked deals with Sophia Genetics, the University of Cambridge, and Optellum to improve early diagnosis of cancer with genomics and AI. Breast Cancer Therapy Response Predicted by Multiomic Machine Learning Model A team led by researchers at the University of Cambridge analyzed more than 160 pre-treatment tumor biopsies to identify features linked to treatment response. GE Healthcare, University of Cambridge Team on AI-Based Precision Oncology Building on earlier work supported by the Mark Foundation for Cancer Research and Cancer Research UK, the partners will create an app to aggregate and analyze clinical, genomic, and imaging data. Evolution of Dengue Virus Antigens Reflected in Outbreaks in Thailand An international team sequenced 1,944 dengue virus isolates collected in Bangkok over 20 years as part of an effort to follow DENV antigen evolution. Thyroid Size, Function in Children Linked to Nutrition-Related DNA Methylation Mark A trial in Gambia suggests PAX8 gene methylation in 2-year-olds corresponds to thyroid volume, hormone production, and physical features later in childhood. Oct 27, 2021 Relationship of Sitting Bull Descendant Verified With Ancient DNA From Lock of Hair Oct 20, 2021 Woolly Mammoths Died Out After Climate Shift Eliminated Food Source, Environmental DNA Study Finds Oct 13, 2021 Chronic Liver Disease Genome Sequences Point to Recurrent Mutations in Metabolic Genes Sep 3, 2021 Europe's Genomics Community Wrestling With Uncertainty Presented by Privacy Legislation Premium Jul 7, 2021 Rare Mutations Associated With Significantly Higher Risk of Type 2 Diabetes in New Study Mar 31, 2021 Type 1 Diabetes Onset Preceded by Gene Expression Changes Mar 10, 2021 Polygenic Risk Score Reporting Standards Developed Feb 5, 2021 Childhood Cancer Study Reveals Pan-Neuroblastoma Cell State Jan 21, 2021 Breast Cancer Risk Gene Associations Refined in Large-Scale Studies Dec 8, 2020 Single-Cell Transcriptome Study Links Gut Development, Pediatric Crohn's Disease Nov 23, 2020 Rare Variant Study Suggests Blood Pressure Traits May Have Ties to Development, Heart Conditions Sep 16, 2020 Viking Age Human Migrations Untangled Through Ancient DNA Analysis Sep 8, 2020 Early Copy Number Changes Predict Progression of Barrett's Esophagus to Esophageal Cancer Sep 3, 2020 Blood Cell Traits Linked to Individual Loci, Polygenic Contributors in International Studies Jul 21, 2020 Less Painful Childbirth Associated With Rare Variant in Ion Channel Gene Jun 25, 2020 Inivata Demonstrates Potential of ctDNA Assay for Cancer Recurrence, MRD Applications Premium Jun 24, 2020 Whole-Genome Sequencing Study Identifies Four Novel Disease-Causing Variants Jun 23, 2020 Patient-Specific ctDNA Detection Method Could Improve MRD Monitoring for Cancer Recurrence Premium Jun 11, 2020 Diversity Problem Hinders Adoption of Polygenic Risk Scores, According to ESHG Panel Jun 8, 2020 Microbiotica, Cambridge Researchers to Study Microbiome Impact on Immunotherapy Response Load More Breaking News Dilated Cardiomyopathy Gene Mutations Point to Possible Therapeutic Strategy Ginkgo Bioworks Acquires Massachusetts COVID-19 Testing Firm Mainz Biomed Taps DCN Dx to Aid European Study of Enhanced ColoAlert Assay Parse Biosciences Partners With Research Instruments for Southeast Asia Distribution Thermo Fisher, Oncocyte Ink Development, Comarketing Deal for Cancer IVDs Yourgene Health Enters Three-Year £5M Term Loan Facility The Scan And a Fourth? A fourth dose of the Pfizer-BioNTech SARS-CoV-2 vaccine in an Israeli study increased antibody levels but did not prevent Omicron variant infections, according to the Financial Times. For Better Science Software A virtual institute funded by former Google CEO Eric Schmidt's philanthropy aims to lure software engineers to academia, Science reports. Recommendation Explanations The New York Times writes that the US Centers for Disease Control and Prevention is straining to both make and explain decisions based on limited information. Genome Research Papers on De Novo Mutation Rates, Polyploid Genotyping, Oncogene Epigenomic Translocation In Genome Research this week: de novo mutations rates in hemoglobin subunits, analysis of variant calling methods for polyploid plants, and more.