University of Bristol
Sibling-Informed GWAS Distinguishes Between Direct Genetic Effects on Traits, Biases
With data on 178,086 siblings, researchers searched for direct genetic contributors to 25 phenotypes, comparing them to population-based GWAS signals.
Ovarian Cancer Subtypes, Endometriosis Show Genetic Overlap in Study
Endometriosis risk loci appeared to be linked to risk of specific epithelial ovarian cancer histotypes, with shared underlying processes and pathways.
Testosterone-Related Genetic Variants Don't Influence Socioeconomic Status, Study Finds
After identifying testosterone-linked variants in UK Biobank participants, investigators used Mendelian randomization to assess testosterone ties to socioeconomic measures.
DNA Methylation at Certain Sites May Have Causal Effect on Lung Function, Study Finds
The researchers' findings suggest that methylation at those sites might have their effect on lung function through its effect on smoking behaviors.
Canker Sore Risk Influenced by Nearly 100 Genetic Variants, GWAS Reports
University of Bristol researchers unearthed variants that implicate the immune system in the risk of developing mouth ulcers.