University of Alabama at Birmingham

This Week in PNAS

In PNAS this week: Takayasu arteritis risk loci, gene expression-based subgroups of B-cell precursor acute lymphoblastic leukemia, and more.

The projects are organized by the Eliminate Cancer Initiative, the National Brain Tumor Society, and the Pediatric Brain Tumor Foundation.

A University of Alabama at Birmingham-led team has found that mutations within five NF1 codons are linked to an increased likelihood of severe neurofibromatosis symptoms.

The HPOs will receive $13.8 million to enroll people interested in the All of Us program, gather participant health information, and help retain participants.

The grant will fund a collaboration investigating whether genomic signatures and other biomarkers can be used in clinical diagnosis and monitoring of kidney cancer.

The number of institutions offering clinical exome or genome tests to healthy individuals keeps increasing, but the practice remains controversial among medical experts.

The Alabama Genomic Health Initiative aims to recruit participants from every county in the state and provide genomic analysis and interpretation free of charge. 

The organizations in the consortium will identify, characterize, and catalog human biological molecules affected by physical activity in volunteer biosamples.

The agency has awarded five-year grants to three research institutions to promote education in genomic medicine among physicians and biomedical scientists.

Genome-wide association and other genetic studies hint at variants increasing subsequent neoplasm risk in individuals treated for cancer during childhood.

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Chinese state news agency Xinhua reports that a preliminary investigation has found He Jiankui performed his gene-editing work illegally.

John Mendelsohn, a former president of the University of Texas MD Anderson Cancer Center, has died, the New York Times reports.

Identical twins receive different estimates of ancestry from the same direct-to-consumer genetic testing firms, CBC reports.

In PNAS this week: chromosomal features of maize, adaptations in the vinous-throated parrotbill, and more.