University of Adelaide Exome Sequencing for Cerebral Palsy Has Sufficient Diagnostic Yield for First-Tier Test A meta-analysis of prior studies found that the diagnostic yield of exome sequencing for cerebral palsy exceeded 31 percent, similar to other neurodevelopmental disorders. Ancient Genomes from Bohemia Point to Complex Population Encounters in Central Europe With 271 new or previously sequenced genomes from Bohemia, researchers followed population dynamics in the region between some 3,600 to 6,900 years ago. Ancient Caucasus Populations Profiled Researchers sequenced 45 individuals from the Caucasus and steppe region between 3,500 and 6,500 years ago, teasing out distinct populations and shared relationships. European PEP-NET Consortium Aims to Integrate Epigenetic Data With Mathematical Models Premium Participants aim to use predictive modeling to better understand epigenetic mechanisms, while encouraging the development of new technologies and therapies. Team Debuts Method for Assembling Phased Genomes From PacBio, Hi-C Data Premium With FALCON-Phase, investigators used PacBio long reads and Hi-C data from Phase Genomics to assemble a haplotype-phased, diploid genome for a hybrid bull. Nov 9, 2017 Lithium Response in Bipolar Disorder Linked to Schizophrenia-Related Variants Oct 18, 2016 Ancient DNA Study Sheds Light on European Bison Origin, Explains Early Cave Art Jun 17, 2016 Ancient Mitochondrial DNA Provides Clues to Ice Age Megafauna Extinction Causes Jun 1, 2016 Ancient Peruvian Sequence Data Argue Against Population Replacement by Wari Empire Nov 23, 2015 Team Seeks Signs of Early Agricultural Adaptation in Hundreds of Ancient Genomes Jul 23, 2015 Ancient DNA Analysis Suggests Rapid Warming, Human Activity Drove Large Species to Extinction Apr 25, 2013 Genomics in the Journals : Apr 25, 2013 Feb 18, 2013 Ancient Plaque Provides Clues to Diet's Effects on Human Mouth Microbiome Aug 27, 2009 Nationwide $828K Proteomics Project Begins in Australia Targeting Multiple Sclerosis Premium Mar 2, 2009 BioRegion Newsmakers: Mar 2, 2009 Premium Breaking News SARS-CoV-2 Variants of Concerns Evolved to Modify Host Immune Response, Multiomics Study Shows People in the News at GA4GH, Mercy BioAnalytics, Deepcell, One Biosciences New Products Posted to GenomeWeb: Clinical Microbiomics, Integra Biosciences, DNAstack, Bruker Angolan Namib Desert Population Analysis Uncovers New Ancestry Group With Deep Divergence Cedars-Sinai Sets Up $25M Single Cell Precision Medicine Center The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.