"We often try to have these heroic 50,000-patient studies out there. Really, a little bit of biological plausibility is all that is needed," said Howard McLeod, head of the Pharmacogenetics in Every Nation Initiative.
An international commission is to develop a report on how researchers, clinicians, and regulators should evaluate the clinical applications of human germline genome editing.
In Genome Research this week: repetitive element deletion linked to altered methylation and more in form of muscular dystrophy; human contamination in draft bacterial and archaeal genomes; and more.
